by Vincent Racaniello on February 7, 2010
Vincent, Alan, and Rich review recent outbreaks of mumps in the UK, US, and Israel, protection of mice against 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 vaccines, and a virus-like particle vaccine for chikungunya virus.
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Download TWiV #69 (59 MB .mp3, 82 minutes)
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Links for this episode:
Weekly Science Picks
Rich John Moran Florida Nature Photography
Alan Periodic Table of Videos
Vincent The Protein Databank Educational Resources
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by Vincent Racaniello on February 1, 2010
Vincent, Alan, and Rich are enthralled by movies of vaccinia virus plaque formation, then consider how repulsion of superinfection virions leads to rapid virus spread, and a therapeutic prostate cancer vaccine.
This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S.
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Download TWiV #68 (58 MB .mp3, 80 minutes)
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Links for this episode:
Weekly Science Picks
Rich Foundations of Virology – PowerPoint by Frederick A. Murphy (bio/interview pdf)
Alan Spoonful of Medicine – Nature Medicine blog
Vincent The Feynman Lectures (thanks Ilya!)
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by Vincent Racaniello on January 24, 2010
Vincent, Alan, and Marc talk about chronic wasting disease of deer caused by prions, blocking the semen-derived enhancer of HIV infection with surfen, and making green transgenic rabbits using a lentiviral vector.
This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S.
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Download TWiV #67 (64 MB .mp3, 88 minutes)
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Links for this episode:
Weekly Science Picks
Marc Association of Science-Technology Centers Passport Program
Alan Zooniverse
Vincent Grand Rounds at the Mailman School of Public Health
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by Vincent Racaniello on January 17, 2010
Vincent and Dickson continue virology 101 with a discussion of information flow from RNA to DNA, a process known as reverse transcription, which occurs in cells infected with retroviruses, hepatitis B virus, cauliflower mosaic virus, foamy viruses, and even in uninfected cells.
This episode is sponsored by Data Robotics Inc. To receive $50 off a Drobo or $100 off a Drobo S, visit drobostore.com and use the promotion code VINCENT.
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Download TWiV #66 (50 MB .mp3, 68 minutes)
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Links for this episode:
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Vincent Joint UN Programme on HIV/AIDS
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by Vincent Racaniello on January 10, 2010
Vincent, Alan, and Matt discuss a project to study the RNA virome of Northeastern American bats, failure to detect XMRV in UK chronic fatigue syndrome patients, and DNA of bornavirus, an RNA virus, in mammalian genomes.
This episode is sponsored by Data Robotics Inc. To receive $50 off a Drobo or $100 off a Drobo S, visit drobostore.com and use the promotion code VINCENT.
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Download TWiV #65 (58 MB .mp3, 80 minutes)
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Links for this episode:
Weekly Science Picks
Matt 100 Incredible lectures from the world’s top scientists
Alan The Amateur Scientist CD
Vincent The Immortal Life of Henrietta Lacks by Rebecca Skloot
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by Vincent Racaniello on January 3, 2010
Vincent, Alan, and Rich discuss ten compelling virology stories of 2009.
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Download TWiV #64 (68 MB .mp3, 94 minutes)
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Ten virology stories of 2009:
- Pandemic influenza: Swine-origin H1N1 virus (TWiV 36)
- XMRV, prostate cancer, and chronic fatigue syndrome (TWiV 50, 55)
- AIDS vaccine ’success’ (TWiV 51)
- Colony collapse disorder (TWiV 46, 49)
- AIDS-like disease in wild chimps (TWiV 45)
- Diverse viral community in Antarctic lake (TWiV 58)
- Polyomavirus seroepidemiology in humans (TWiV 26)
- Poxvirus threatens UK red squirrels (TWiV 63)
- Polio spreads from Nigeria (TWiV 29)
- How mosquitoes survive Dengue virus infection (TWiV 21)
Picture book on viruses for kids (Thanks Soraia!)
Weekly Science Picks
Rich Surely You’re Joking, Mr. Feynman! by Richard P. Feynman, Ralph Leighton, Edward Hutchings, and Albert R. Hibbs
Alan Spaceweather.com
Vincent The Art and Politics of Science by Harold Varmus
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by Vincent Racaniello on December 20, 2009
Vincent, Alan, and Rich talk about US government contract for freeze-dried smallpox vaccine, red squirrels in the UK threatened by poxvirus, and Marseillevirus, another DNA virus from amoebae built for comfort and speed.
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Download TWiV #63 (64 MB .mp3, 89 minutes)
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Links for this episode:
Weekly Science Picks
Rich Infectious Awearables
Alan Darwine
Vincent Microbial Art
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by Vincent Racaniello on December 13, 2009
Vincent, Dickson, and Alan discuss STEP HIV-1 vaccine failure caused by the adenovirus vector, presence of West Nile virus in kidneys for years after initial infection, adaptation of the influenza viral RNA polymerase for replication in human cells, and the significance of the D225G change in the influenza HA protein.
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Download TWiV #62 (47 MB .mp3, 66 minutes)
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Links for this episode:
Weekly Science Picks
Dick Smallpox – The Death of a Disease by DA Henderson
Alan Olympus Bioscapes Digital Imaging Competition
Vincent Microbe Magazine
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by Vincent Racaniello on December 6, 2009
Vincent and Dick muse about the symbiotic bacterium, Wolbachia, that protects flies from viral infection, the origin of 2009 influenza H1N1 virus, and the lure of original antigenic sin.
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Download TWiV #61 (45 MB .mp3, 62 minutes)
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Links for this episode:
Weekly Science Picks
Dick New Guinea Tapeworms and Jewish Grandmothers by Robert S. Desowitz
Vincent Information is Beautiful – is swine flu vaccine safe?
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by Vincent Racaniello on November 29, 2009
Vincent and Dick continue Virology 101 with a discussion of how RNA viruses produce mRNA and replicate their genomes.
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Download TWiV #60 (51 MB .mp3, 71 minutes)
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Links for this episode:
Weekly Science Picks
Dick The Double Helix by James D. Watson
Vincent Worms and Germs Blog
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Below is a video of TWiV 60, which highlights the diagrams I referred to during the podcast.
Download TWiV 60 video. These videos are slightly larger (800 x 512) than the flash version shown above
186 MB .mov video file
584 MB .wmv video file