TWiV 330: A swinging gate

March 29, 2015

Swinging gateHosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

The TWiVers explain how a protein platform assists the hepatitis C virus RNA polymerase to begin the task of making viral genomes.

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Timestamps by Jennifer. Thank you!

Weekly Science Picks 1:32:25

Alan – X-Flare 2.1 captured
Rich – Volvo ocean race drops research buoys (YouTube)
Kathy – Nature double-blind peer review
Dickson – Largest cave in the world
Vincent – New program for early-career scientists

Listener Pick of the Week

Michael – Space Engine and Kerbal Space Program
Varun CN – Incognito by David Eagleman

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Wash Your HandsHosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

The TWiV team reviews identification of immune biomarkers in CFS/ME patients, and how a cell nuclease controls the innate immune response to vaccinia virus infection.

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Timestamps by Jennifer. Thank you!

Weekly Science Picks 1:35:10

Alan – NASA Solar Dynamics Observatory video
Rich – Mutagenic chain reaction (Video: Genome editing with CRISPR)
Kathy – Science Ambassadors Program
Dickson – Street Art
Vincent – End Polio Now

Listener Pick of the Week

Ross – Three PhD Comics on Nature vs Science (one, two, three)
Ricardo – Demographic Party Trick

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splicingHosts: Vincent RacanielloDickson DespommierAlan DoveRich Condit, and Kathy Spindler

The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing.

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Weekly Science Picks

Alan – Positively Negative (PLoS One)
Rich – ISS assembly (YouTube)
Kathy – Ancient trees
Dickson – Carolyn Porco
Vincent – Tony Fauci on Ebola outbreak (YouTube)

Listener Pick of the Week

David – Shot by Shot
Judi – The Power of Herd Immunity

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Weird machineHosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

The eTWiVicators review evidence that the HIV-1 group O epidemic began with a single cross-species transmission of virus from western lowland gorillas.

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Weekly Science Picks

Alan – California bill to eliminate personal vaccine exemptions
Rich – Kepler observatory (Kepler-186f)
KathyUSGS disease map
DicksonPhilosphy of Microbiology by Maureen O’Malley
Vincent – Nautilus

Listener Pick of the Week

Ken – Life in our phage world (online, book party); All about that base
Neal – Gilles van Cutsem at CROI
Ricardo – Flow hive

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BrandonHosts: Vincent Racaniello, Alan Dove, and Rich Condit

The sternutating TWiVers discuss preventing infection of cells and animals by a soluble CD4-CCR5 molecule that binds to HIV-1 virus particles.

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Weekly Science Picks

Alan – Toms River by Dan Fagin
Rich – Spin by Robert Charles
Vincent – FCC votes for net neutrality (ArsTechnica)

Listener Pick of the Week

Neal – Why doesn’t everyone get the flu vaccine?
Fernando – Zombie Jonas Salk hunts idiots
NevaPhysicists in biology

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TWiV 325: Wildcats go viral

February 22, 2015

TWiV 325Host: Vincent Racaniello

Guests: Rollie Clem and Lorena Passarelli

Vincent visits the ‘Little Apple’ and speaks with Rollie and Lorena about their work on mosquito-born viruses and baculoviruses.

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Viruses in the miRHosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

Guest: Lee Feinman

Lee joins the TWiV team to discuss the value of post-doctoral training, and how a cellular microRNA assists in the replication of hepatitis C virus.

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Weekly Science Picks

Lee – Furthering America’s Research and Upgoer five and six
Alan – 
Best snow shovel
Rich – Ripple tank
KathyFractals
Dickson – World Press Photo Contest 2015
Vincent – What to do about antivax politicians and physicians

Listener Pick of the Week

Patricia – Future of Bioscience Graduate & Postdoc training
Paul – This is my son Griffin, and he may have measles

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skid loader full of viromesHosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

The family TWiVidae discuss changes in the human fecal virome associated with Crohn’s disease and ulcerative colitis.

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Weekly Science Picks

Alan – Sitesucker
RichSnake picked wrong dinner
Dickson – Sapporo Snow Festival
Vincent – Mapping NYC subway DNA

Listener Pick of the Week

Gretchen – Scientific way to cut a cake
Leslie – Principles of Virology, Second Edition

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infectious inboxHosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Kathy Spindler

The TWiVodes answer listener email about hantaviruses, antivirals, H1N1 vaccine and narcolepsy, credibility of peer review, Bourbon virus, influenza vaccine, careers in virology, and much more.

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Weekly Science Picks

Alan – Boom by Tony Horowitz
Kathy – Octopus supermom
DicksonMacrophotography
Vincent – Virology lectures 2015 (virology blog and YouTube)

Listener Pick of the Week

Paul – Illsville: Fight the Disease
Ramon – Vaccinate! Do it for the testicles
SandraWho can you trust?

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TWiV 321: aTRIP and a pause

January 25, 2015

Going down the rabbit holeHosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Kathy Spindler

Guest: Paul Duprex

Paul joins the TWiV team to discuss the current moratorium on viral research to alter transmission, range and resistance, infectivity and immunity, and pathogenesis.

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Weekly Science Picks

Alan – In a Sunburned Country by Bill Bryson
PaulSaving the lives of our dogs (blog post)
Kathy – New all-female Lego set
DicksonFemale storm-chaser
Vincent – Despommier Photo Art

Listener Pick of the Week

Jacob – Exaggeration in news and press releases (BMJ)
Peter – Quartet game (photos: one, two, three, four, five)

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