TWiV 51: ALVAC-HIV and AIDSVAX B/E

Hosts: Vincent Racaniello, Dick Despommier, and Alan Dove

Vincent, Dick, and Alan (with a cameo appearance by Rich Condit) review the world’s largest Phase III study of a complex HIV vaccine candidate in Thailand, immunization of salmon against infectious salmon anemia virus, and an outbreak of blueberry shock virus in Michigan.

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Click the arrow above to play, or right-click to download TWiV #51 (60 MB .mp3, 84 minutes)

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Links for this episode:

• HIV vaccine shows promise for the first time – description of the program, FDA background document (pdf), NEJM review on why AIDS vaccine is difficult (pdf), and arguments for the trial
• Chile immunizes salmon (USGS article on the virus, pdf)
• Blueberry virus strikes Michigan research center (information on the disease and the virus)
• Rotavirus seasonality (thanks Didier!)
• Viruses and the tree of life at virology blog
• Big brains have evolved twice (thanks Arsen!)

Weekly Science Picks
Alan Bat Rabies and Other Lyssavirus Infections
Dick Boosting Vaccines: The Power of Adjuvants (Scientific American; subscription required)
Vincent The Ig Nobel Prizes by Marc Abrahams

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Tagged as: AIDS, AIDSVAX, ALVAC-HIV, blueberry shock virus, H1N1, HIV, influenza, isav, rotavirus, salmon, seasonality, swine flu, viral, virology, virus