TWiV 223: EEEV and the serpent

March 10, 2013

NA defective fluHosts: Vincent Racaniello, Alan Dove, and Kathy Spindler

Vincent, Alan, and Kathy discuss new influenza virus NA inhibitors, detection of EEEV antibody and RNA in snakes, and replication of the coronavirus EMC in human airway epithelial cells.

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Weekly Science Picks

Kathy – Finkbeiner test and Women in Science
Alan – New flu vaccine efficacy study (CDC)
Vincent –  Threading the NEIDL video

Listener Pick of the Week

Steve - Prof. Joan Steitz on viral RNA
Ed – Archiving history of molecular biology: Press release, video, CSHL archives and videos

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TWiV 222: Jumpin’ Jack Flash, it’s a GAS GAS GAS

March 3, 2013

cyclic GAMPHosts: Vincent Racaniello, Rich Condit, Dickson Despommier, Alan Dove, and Kathy Spindler

The complete TWiV team discusses the amazing finding that cyclic GMP-AMP synthase is a cytosolic innate immune DNA sensor.

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Weekly Science Picks

Kathy – Graphene batteries
Alan – How do we get cures? (YouTube)
Rich – Explosive breach of Condit Dam (Vimeo)
Vincent –  10 things you can do to support open access (Tree of Life)

Listener Pick of the Week

Mark - The real story of Stuxnet
John – D-connector virus

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TWiV 221: Bunya there, done that

February 24, 2013

SBV infectious DNAHosts: Vincent Racaniello, Dickson Despommier, and Kathy Spindler

Vincent, Dickson, and Kathy review two emerging bunyaviruses, SFTSV and SBV.

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Weekly Science Picks

Kathy – Winners, 2012 Science & Engineering Visualization Challenge
Vincent –  The Operator and Dr. Oz’s Problem

Listener Pick of the Week

Shane - OpenPCR
John – Python

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TWiV 220: Flu watches the clock while T7 gets a CAT scan

February 17, 2013

T7 random walkHosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler

Vincent, Rich, Alan, and Kathy discuss regulation of influenza virus replication by splicing, and the bacteriophage T7 random walk.

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Weekly Science Picks

Kathy – Journal of Virology Image Gallery
Rich – Phage T7 Genetics and Physiology and slab gels
Alan – PeerJ (press release)
Vincent –  Virologia en Español

Listener Pick of the Week

Dave – Thingiverse pathogens and proteins 

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TWiV 219: Fauci pharmacy

February 10, 2013

Anthony Fauci, MDHosts: Vincent Racaniello, Rich Condit, and Anthony S. Fauci

Vincent and Rich meet up with Anthony S. Fauci, MD, Director of the National Institute of Allergy and Infectious Diseases.

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TWiV 217: I just flu in and my arms are shot

January 27, 2013

vaccine vialHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Dickson Despommier

Vincent, Alan, Rich, and Dickson review influenza vaccines.

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Weekly Science Picks

Rich – Repoopulate (original article), Robogut (new clinical trial)
Alan – WTF, Evolution?
Dickson – The Beauty and Benefits of Science
Vincent – Supercomputing modeling of poliovirus

Listener Pick of the Week

Bjorn, Marshall, Meaghan – Glass sculptures of Luke Jerram

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TWiV 216: Processing VIRALGUUAACACCAGRNA

January 20, 2013

splicingHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

Vincent, Alan, Rich, and Kathy resume the virology 101 series with a discussion of RNA capping, splicing, and export.

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Weekly Science Picks

Rich – Linus Pauling’s explanation of science (YouTube)
Alan – Underwater experiments
Kathy – I’m a virus (YouTube)
Vincent – Stem cells (Bizarro Comics)

Listener Pick of the Week

Tom - The President’s Analyst
Danielle – Overly honest methods (HuffPost and ASBMB Today)

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TWiV 215: Illuminating rabies and unwrapping a SARI

January 13, 2013

Virus in the gardenHosts: Vincent Racaniello, Alan Dove, and Kathy Spindler

Vincent, Alan, and Kathy review the finding that rabies virus infection alters but does not kill neurons, and provide an update on the novel coronavirus in the Middle East.

 

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Weekly Science Picks

Alan – I’m a Scientist – The Film
Kathy – Humorous units of measurement (Wikipedia)
Vincent – Open access must enable open use (Nature)

Listener Pick of the Week

Tarwin - Plague Inc.

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TWiV 214: This is your brain on polyomavirus

January 6, 2013

raccoon tumorHosts: Vincent Racaniello, Alan Dove, and Kathy Spindler

Vincent, Alan, and Kathy discuss how coagulation factor X binding to adenovirus activates the innate immune system, and a novel polyomavirus associated with brain tumors in raccoons.

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Weekly Science Picks

Alan – Parasite of the Day
Kathy – Tour of International Space Station
Vincent – Earth as Art

Listener Pick of the Week

Robin - Angell on Big Pharma
Michael – Flu jokes
Jim – Database of Ted talks; Downloadable Ted Talks

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