Hosts: Alan Dove and Rich Condit

Alan and Rich tackle the discovery of bacteriophages, and treating influenza by calming the cytokine storm.

Click the arrow above to play, or right-click to download TWiV 145 (63 MB .mp3, 87 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Twort on the nature of ultra-microscopic viruses (Lancet)
• Who discovered bacteriophage? (pdf, Bact Rev)
• Calming cytokine storm to treat influenza (PNAS)
• TWiV on Facebook
• Letters read on TWiV 145

Weekly Science Picks

Alan – AT&T Tech Channel
Rich – Smallpox and its eradication (pdf)

Listener Pick of the Week

Asif – Science Photo Library

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Alan Dove

Vincent, Rich, and Alan discuss a method for identifying viruses of individual environmental bacteria, and the using a picornavirus for oncotherapy.

Click the arrow above to play, or right-click to download TWiV 142 (69 MB .mp3, 95 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Probing individual bacteria for their viruses (Science)
• Looking in vivo at virus-bacterium interactions (ScienceDaily)
• Integrated fluidic circuit (Fluidigm)
• Oncotherapy with Seneca Valley Virus (Clin Cancer Res)
• Epidemiology of Seneca Valley virus (pdf)
• Senecavirus at ViralZone
• Small cell lung cancer (NCBI)
• ECOG performance status
• RECIST
• TWiV on Facebook
• Letters read on TWiV 142

Weekly Science Picks

Alan – Germlines podcast
Rich – science360
Vincent – Google+

Listener Pick of the Week

Angus – Science Weekly with Alok Jha

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Roger Hendrix, Rachel Katzenellenbogen, and Harmit Malik

Vincent and guests Rachel Katzenellenbogen, Roger Hendrix, and Harmit Malik recorded TWiV #135 live at the 2011 ASM General Meeting in New Orleans, where they discussed transformation and oncogenesis by human papillomaviruses, the amazing collection of bacteriophages on the planet, and the evolution of genetic conflict between virus and host.

Click the arrow above to play, or right-click to download TWiV #135 (63 MB .mp3, 97 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Papillomavirus E6 proteins (Virology)
• Diversity of mycobacteriophages (PLoS One)
• Adaptive evolution of tetherin (J Virology)
• TWiV on Facebook
• Letters read on TWiV 135
• Video of this episode – view below

Weekly Science Picks

Roger – Atomic structure of adenovirus by cry0-EM (Science)
Harmit – Syncytin knockout mice show role for endogenous retroviral gene (PNAS)
Vincent – Free science, one paper at a time by David Dobbs

Listener Pick of the Week

Mark  - Shot by Shot

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Click the arrow above to play, or right-click to download TWiV #98 (58 MB .mp3, 80 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• MLV-related sequences in blood of CFS patients (commentary)
• Laboratory inventories for poliovirus containment
• Viral batteries for the military (abstract) – also see TWiV 28
• Human rabies, Kentucky/Indiana, 2009
• Letters read on TWiV 98

Weekly Science Picks

Alan – NCBI ROFL
Rich – The Great Bridge by David McCullough
Vincent – Dr. Rous’ Prize-Winning Chicken

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich consider the end of the influenza H1N1 pandemic, dengue in Florida, vaccinia virus infection in Brazilian monkeys, and viruses in the faecal microbiota.

Click the arrow above to play, or right-click to download TWiV #95 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• WHO declares end of influenza H1N1 pandemic
• CDC’s FluView
• WHO global monitoring of influenza
• Locally acquired dengue in Key West, Florida (MMWR)
• CDC page on dengue
• Vaccinia virus infection in monkeys of the Brazilian Amazon
• Dam site where animals were collected for vaccinia study (Google maps)
• Rich’s article: Whence feral vaccinia?
• Viruses in the faecal microbiota of monozygotic twins and their Mothers (Nature)
• New Yorker article The Treatment (thanks, Jim!)
• Letters read on TWiV 95

Weekly Science Picks

Alan – Families Fighting Flu
Rich – Food, Inc.
Dickson –  Fuel
Vincent – MIT Open Courseware
Michael –  Waiting for Superman and Can Science Feed the World? (Nature)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Graham Hatfull

Vincent, Alan, and Rich hear from Professor Graham Hatfull how students in the Phage Hunters Integrating Research and Education (PHIRE) program learn about scientific inquiry by doing research on bacteriophages.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo.

To enter a drawing to receive 50% off the manufacturers suggested retail price of a Drobo S or FS at drobostore.com, fill out the questionnaire here.

Click the arrow above to play, or right-click to download TWiV #87 (62 MB .mp3, 86 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Bacteriophage Research: Gateway to learning science
• Mycobacterium smegmatis at NCBI
• Prof. Steve Cresawn
• Scientist infected with computer virus (thanks, Jason!)
• The Invisible ABCs
• Letters read on TWiV 87

Weekly Science Picks

Rich - CDC Public Health Image Library
Alan – Great Microbiologists – A Lego Movie
Vincent - March of the Microbes by John L. Ingraham
Graham – Coral Reefs in the Microbial Seas by Forest Rohwer

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich answer listener questions about maternal infection and fetal injury, viral gene therapy, eyeglasses and influenza, filtering prions from blood, eradication of rinderpest, Tamiflu resistance of H1N1 influenza, bacteriophages and the human microbiome, H1N1 vaccine recalls, human tumor viruses, RNA interference, and junk DNA.

This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #71 (63 MB .mp3, 88 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• Maternal infection and fetal neurological injury
• Filtering prions from blood (prion capture technology)
• Eradication of rinderpest (Merck veterinary manual)
• Podcasts from Life in the Universe course
• Immune Attack video game
• H1N1 review article and Holmes on genetic hijacking
• Podcast on Merck vaccines
• Ft. Lee NJ snowed in (jpg)

Weekly Science Picks

Dickson and Alan NSF/AAAS Science and Engineering Visualization Challenge
Rich Foundation by Issac Asimov
Vincent Natural Obsessions by Natalie Angier

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and Lynn Enquist

Vincent speaks with Lynn Enquist about his career in virology, moving from academia to industry and back. Along the way he did pioneering research on bacteriophage, participated in the birth of recombinant DNA technology, and studied herpesviruses.

Sponsor: Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #54 (63 MB .mp3, 87 minutes)

Subscribe to TWiV in iTunes, by the RSS feed, or by email

Links for this episode:

• Holliday junction
• Asilomar Conference on Recombinant DNA
• Restriction enzymes
• Movies of herpesvirus movement in nerve cells
• The ‘other‘ Enquist lab
• Can you find the TWiV 54 hosts in this photo?

Weekly Science Picks
Lynn Francis Crick: Hunter of Life’s Secrets by Robert Olby
Vincent ViralZone

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss to delicious and tagging them with to:twivpodcast.

Hosts: Vincent Racaniello, Dick Despommier, and Alan Dove

Vincent, Dick, and Alan talk about Nobel prizes for telomere research, bacteriophages that protect aphids from wasps, salicylates and pandemic influenza mortality, and hand washing.

Sponsor: Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #53 (45 MB .mp3, 62 minutes)

Subscribe to TWiV in iTunes, by the RSS feed, or by email

Links for this episode:

• Nobel Prizes for telomere research
• Bacteriophages encode toxins that protect aphids from wasps
• 14 year old dies after receiving HPV vaccine
• Salicylates and pandemic influenza mortality
• Canadian microbiologist says hand washing is not proven to prevent influenza
• Surgical mask vs N95 respirator for preventing influenza
• Americans unsure about receiving pandemic H1N1 influenza vaccine
• DnaTube (thanks Jim!)
• Laboratory Director certification (pdf – thanks Megan!)
• Plant production of pharmaceuticals (pdf one and pdf two – thanks Ed!)

Weekly Science Picks
Alan scienceline
Dick Younger by Judith Sulzberger MD
Vincent FluView

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also send articles that you would like us to discuss to delicious and tagging them with to:twivpodcast.

Hosts: Vincent Racaniello and Dick Despommier

Vincent and Dick discuss influenza virus-like particle vaccines produced in insect and plant cells, rapid sharing of influenza research, and answer listener questions about cytomegalovirus, viral evolution and symbiosis and much more.

Sponsor:  Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #47 (51 MB .mp3, 71 minutes)

Links for this episode:

Weekly Science Picks
Vincent Bionumbers
Dick Ocean: An Illustrated Atlas by Sylvia A. Earle, Linda K. Glover

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast

Subscribe to TWiV in iTunes, by the RSS feed, or by email