Hosts: Vincent Racaniello, Rich Condit, and Alan Dove

Vincent, Alan, and Rich review ten compelling virology stories of 2011.

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Click the arrow above to play, or right-click to download TWiV 164 (60 MB .mp3, 99 minutes).

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Ten virology stories of 2011:

1. XMRV, CFS, and prostate cancer (TWiV 119, 123, 136, 150)
2. Influenza H5N1, ferrets, and the NSABB (TWiV 159)
3. The Panic Virus (TWiV 117)
4. Polio eradication (TWiV 127, 149)
5. Viral oncotherapy (TWiV 124, 131, 142, 156)
6. Hepatitis C virus (TWiV 130, 137, 141)
7. Zinc finger nuclease and HIV therapy (TWiV 144)
8. Bacteria help viruses (TWiV 154)
9. Human papillomaviruses (TWiV 126)
10. Combating dengue with Wolbachia (TWiV 115, 147)

Links for this episode:

• Honorable mention: Color me infected (TWiV 115)
• Lo-Alter retraction (PNAS)
• Propose an ASM General Meeting session
• TWiV on Facebook
• Letters read on TWiV 164

Weekly Science Picks

Rich - Fundamentals of Molecular Virology by Nicholas H. Acheson
Alan – Fetch, with Ruff Ruffman
Vincent – Year end reviews at Rule of 6ix and Contagions

Listener Pick of the Week

Garren – Trillion-frame-per-second video
Judi – iBioMagazine
Ricardo – Brain Picking’s 11 best science books of 2011

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Dickson Despommier

Vincent, Dickson, and Rich meant to do an all-email episode, but first they review results of the Blood XMRV Scientific Research Working Group, and partial retraction of the paper associating XMRV with chronic fatigue syndrome.

With this episode TWiV is three years old.

Click the arrow above to play, or right-click to download TWiV 150 (56 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Partial retraction (Science)
• Failure to confirm (Science)
• False positive (Science)
• Why a partial retraction? (Retraction Watch)
• TWiV on Facebook
• Letters read on TWiV 150

Weekly Science Picks

Dickson – The Tree of Life
Vincent – When do you fact-check article content with sources? (take as directed)
Rich – io9

Listener Pick of the Week

Luis – NIH videocasting and podcasting

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Stephen Goff

Retrovirologist Stephen Goff joins Vincent, Rich, and Alan for a discussion of recent papers on the retrovirus XMRV and its association with chronic fatigue syndrome and prostate cancer.

Click the arrow above to play, or right-click to download TWiV #136 (61 MB .mp3, 84 minutes).

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Links for this episode:

• Recombinant origin of XMRV (Science Express)
• No evidence of gammaretroviruses in XMRV-positive CFS patients (Science Express)
• Editorial expression of concern (Science)
• Absence of XMRV in CFS patients (J Virology)
• TWiV on Facebook
• Letters read on TWiV 136

Weekly Science Picks

Alan – The Demon-Haunted World by Carl Sagan
Rich – Trends in annual rates of death (pdf)
Stephen – Unexpected inheritance (PLoS Pathogens)
Vincent – Beyond the human eye

Listener Pick of the Week

Raihan  - Bruce Aylward: How we’ll stop polio for good (YouTube)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes.

Click the arrow above to play, or rightight click to download TWiV #123 (67 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Analysis of XMRV integration sites from human prostate cancer (Retrovirology)
• Integration site preference of XMRV (J Virology)
• The Decline Effect and the Scientific Method by Jonathan Lehrer (New Yorker)
• Why most published research findings are false (PLoS Medicine)
• Cochrane Reviews
• Richard Feynman’s 1974 Caltech Commencement Address (pdf) (thanks, Bill!)
• First virus of Caenorhabditis (PLoS Biology)
• Nodaviruses at ViralZone
• Spandrels (thanks, Welkin!)
• TWiV on Facebook
• Letters read on TWiV 123

Weekly Science Picks

Rich – Einstein: His Life and Universe by Walter Isaacson (Aspen Institute)
Alan – Hi-definition microscopy movies in 3D
Vincent – Stan Maloy interview with Beatrice Hahn on the origins of HIV and malaria

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and David Tuller

Vincent and journalist David Tuller converse about the state of science reporting by the press.

Click the arrow above to play, or right click to download TWiV #119 (43 MB .mp3, 60 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• The four XMRV papers in Retrovirology (one, two, three, four) and a commentary
• David’s recent coverage of ME/CFS in the NY Times (July 2010, August 2010, January 2011)
• MRSA (methicillin-resistant Staphylococcus aureus): The press’ mea culpa
• TWiV on Facebook

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Host: Vincent Racaniello

On episode 99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston, speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure.

Many thanks to Chris Condayan and Ray Ortega of the American Society for Microbiology for recording and editing this episode.

Click the arrow above to play, or right-click to download TWiV #99 (45 MB .mp3, 62 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• 50th ICAAC
• ICAAC daily press conference videos (including Prof. Myra McClure)
• Antigenic cartography
• Antimicrobial properties of copper
• Video of this episode – download .mp4 (1.99 GB) or .wmv (935 MB) or view below

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Click the arrow above to play, or right-click to download TWiV #98 (58 MB .mp3, 80 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• MLV-related sequences in blood of CFS patients (commentary)
• Laboratory inventories for poliovirus containment
• Viral batteries for the military (abstract) – also see TWiV 28
• Human rabies, Kentucky/Indiana, 2009
• Letters read on TWiV 98

Weekly Science Picks

Alan – NCBI ROFL
Rich – The Great Bridge by David McCullough
Vincent – Dr. Rous’ Prize-Winning Chicken

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Ila Singh

Vincent, Alan, and Rich speak with Ila Singh about the new human retrovirus XMRV, and how her laboratory is studying its association with prostate cancer and chronic fatigue syndrome.

Click the arrow above to play, or right-click to download TWiV #94 (56 MB .mp3, 77 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• CFIDS Association of America
• Discovery of XMRV (PLoS Pathogens)
• Detection of XMRV in CFS patients (Science)
• Presence of XMRV in malignant prostate (PNAS)
• Inhibition of XMRV by raltegravir (PLoS One)
• Letters read on TWiV 94

Weekly Science Picks

Alan – The new Federal Register site (see also regulations.gov)
Rich – The Florida Museum of Nautural History Butterfly Rainforest
Vincent – JoVE, the Journal of Visualized Experiments

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and Alan Dove

Vincent and Alan review recent findings on the association of the retrovirus XMRV with ME/CFS, reassortment of 2009 pandemic H1N1 influenza virus in swine, and where influenza viruses travel in the off-season.

Click the arrow above to play, or right-click to download TWiV #89 (56 MB .mp3, 78 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Conflicting XMRV papers on hold
• Leak of PNAS paper
• CDC study on XMRV in CFS patients (Retrovirology) and Science update
• Where influenza viruses travel in the off season (EurekaAlert! and PLoS Pathogens)
• NPR article on Ebola siRNA treatment (thanks, Andreas!)
• Priming mechanism for reovirus entry (thanks, Agyeman-Badu!)
• Wired article on science PR (thanks, Dan!)
• Letters read on TWiV 89

Weekly Science Picks

Alan – Tree of Life graphic
Vincent - TEDx Oil Spill

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and Rich Condit

Vincent and Rich answer listener questions on viruses and gluten allergy, RNA silencing, influenza virus, herpes simplex virus, HIV/AIDS, chronic fatigue syndrome, manicure salons, and the koala tea of Marseilles.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #81 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Virus infections and gluten intolerance on TWiS (thanks Jesper!)
• Viral small RNAs in PLoS Pathogens (thanks Jason!)
• Canadian Summit Awards (thanks Jim!)
• Experimenting with phage at home (thanks Richard!)
• CRISPR discovered by a dairy company (thanks Joel!)
• Expedition to New Guinea to sample bird viruses – movie and blog entry (thanks Henrik!)
• Preventing herpes with arginine and lysine – pdf (thanks Anthony!)
• Chronic fatigue donors face rejection (thanks James!)
• The Koala tea of Marseilles is not strained (thanks Stephen!)
• The other Larson virus cartoon (jpg)
• Letters read on TWiV 81

Weekly Science Picks

Rich Google Chrome browser ‘speed test‘ (and how it was made)
Vincent Inside the Outbreaks by Mark Pendergrast

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.