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	<title>This Week in Virology &#187; crispr</title>
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	<description>A netcast about viruses - the kind that make you sick</description>
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		<title>TWiV 72: Bucket of bolts</title>
		<link>http://www.twiv.tv/2010/03/07/twiv-72-bucket-of-bolts/</link>
		<comments>http://www.twiv.tv/2010/03/07/twiv-72-bucket-of-bolts/#comments</comments>
		<pubDate>Mon, 08 Mar 2010 02:24:29 +0000</pubDate>
		<dc:creator>Vincent Racaniello</dc:creator>
				<category><![CDATA[Netcast]]></category>
		<category><![CDATA[archaea]]></category>
		<category><![CDATA[bacteria]]></category>
		<category><![CDATA[crispr]]></category>
		<category><![CDATA[genome]]></category>
		<category><![CDATA[immune system]]></category>
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		<category><![CDATA[RNAi]]></category>
		<category><![CDATA[TWiV]]></category>
		<category><![CDATA[viral]]></category>
		<category><![CDATA[virology]]></category>
		<category><![CDATA[virus]]></category>
		<category><![CDATA[west nile virus]]></category>

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		<description><![CDATA[Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit This week the TWiV team explains CRISPR/Cas, the immune system of bacteria and archaea, how novel viruses are discovered by deep sequencing of small RNAs, and the relationship between dry weather and outbreaks of West Nile virus infection. This episode is sponsored by Data Robotics [...]]]></description>
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<h3 style="font-size: 1.17em;"><span><strong><span style="font-weight: normal;"><a href="http://www.twiv.tv/wp-content/uploads/2010/03/bucket_bolts.jpg" target="_blank"><img class="alignleft size-medium wp-image-1055" title="Bucket of bolts" src="http://www.twiv.tv/wp-content/uploads/2010/03/bucket_bolts-224x300.jpg" alt="" width="224" height="300" /></a>Hosts</span></strong><span style="font-weight: normal;">:</span><span style="font-weight: normal;"> </span><span style="font-weight: normal;"><span style="font-weight: normal;"><a onclick="javascript:pageTracker._trackPageview ('/outbound/en.wikipedia.org');" href="http://en.wikipedia.org/wiki/Vincent_Racaniello" target="_blank">Vincent Racaniello</a>, <a href="http://medicalecology.org" target="_blank">Dickson Despommier</a>, <a href="http://dovdox.com" target="_blank">Alan Dove</a>, and <a href="http://www.mgm.ufl.edu/faculty/rcondit.htm" target="_blank">Rich Condit</a></span></span></span></h3>
<p>This week the TWiV team explains CRISPR/Cas, the immune system of bacteria and archaea, how novel viruses are discovered by deep sequencing of small RNAs, and the relationship between dry weather and outbreaks of West Nile virus infection.</p>
<p>This episode is sponsored by <a href="http://www.drobo.com/twiv" target="_blank">Data Robotics Inc.</a> Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S.</p>
<p>Win a free Drobo S! Contest rules <a href="http://www.twiv.tv/drobo-contest/" target="_blank">here</a>.</p>

<p>Click the arrow above to play, or right-click to download <a href="http://traffic.libsyn.com/twiv/TWiV072.mp3" target="_blank">TWiV #72</a> (62 MB .mp3, 85 minutes)</p>
<p>Subscribe to TWiV (free) in <a onclick="javascript:pageTracker._trackPageview ('/outbound/phobos.apple.com');" href="http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" target="_blank">iTunes </a>, at the <a href="http://social.zune.net/external/launchclient.aspx?mid=229a09fa-8bb3-40a4-8136-0812d4fb20fa&amp;mtype=Podcast" target="_blank">Zune Marketplace</a>, by the <a href="http://feeds2.feedburner.com/twivmp3" target="_blank">RSS feed</a>, or by <a href="http://www.feedburner.com/fb/a/emailverifySubmit?feedId=2792873&amp;loc=en_US" target="_blank">email</a>.</p>
<p><strong>Links for this episode:</strong></p>
<ul>
<li><a href="http://www.sciencemag.org/cgi/content/abstract/327/5962/167" target="_blank">Review</a> on the CRISPR/cas system of bacteria and archaea</li>
<li>Virus discovery by sequencing small virus-derived RNAs (paper <a href="http://www.pnas.org/content/107/4/1606" target="_blank">one</a> and <a href="http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6WXR-4W4JPXB-4&amp;_user=10&amp;_coverDate=05%2F25%2F2009&amp;_rdoc=1&amp;_fmt=high&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_rerunOrigin=google&amp;_acct=C000050221&amp;_version=1&amp;_urlVersion=0&amp;_userid=10&amp;md5=9a3323863390fe192d864e4ee1529736" target="_blank">two</a>)</li>
<li>Dry weather induces outbreaks of West Nile virus infection (<a href="http://www.biomedcentral.com/1471-2334/10/38" target="_blank">paper</a> and <a href="http://www.biomedcentral.com/1471-2334/10/38/comments" target="_blank">comment form</a>)</li>
<li>Vaccine needle size <a href="http://www.reuters.com/article/idUSTRE61733Z20100208" target="_blank">matters</a></li>
<li>Participate in the <a href="http://www.personalgenomes.org/" target="_blank">Personal Genome Project</a></li>
</ul>
<p><strong>Weekly Science Picks</strong></p>
<p><strong>Dickson</strong> <em>Scientist as Chef</em> by Dickson Despommier (<a href="http://www.twiv.tv/Scientist_as_Chef.pdf" target="_blank">pdf</a>)<br />
<strong>Alan <span style="font-weight: normal;">Networked Organisms and Habitats (NOAH) <a href="http://www.networkedorganisms.com" target="_blank">iPhone app</a></span><br />
</strong><strong>Rich </strong><em><a href="http://astore.amazon.com/virologyws-20" target="_blank">Never Cry Wolf</a> </em>by Farley Mowat<a href="http://zooniverse.org/home" target="_blank"><br />
</a><strong>Vincent <span style="font-weight: normal;"><a href="http://www.microbeworld.org/index.php?option=com_content&amp;view=category&amp;layout=blog&amp;id=103&amp;Itemid=268" target="_blank">The Dish</a></span></strong></p>
<p>Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at <a href="http://www.skype.com" target="_blank">Skype</a>: twivpodcast. You can also post articles that you would like us to discuss at <a href="http://microbeworld.org" target="_blank">microbeworld.org</a> and tag them with <em>twiv</em>.</p>
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