TWiV 74: Influenza with Professor Adolfo Garcia-Sastre

Vincent Racaniello — Mon, 22 Mar 2010 01:10:15 +0000

Hosts: Vincent Racaniello and Adolfo Garcia-Sastre

Vincent speaks with Adolfo Garcia-Sastre about the origin, pathogenesis, and prevention of the 2009 pandemic influenza H1N1 virus.

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Click the arrow above to play, or right-click to download TWiV #74 (34 MB .mp3, 47 minutes)

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Links for this episode:

Influenza virus receptor specificity and disease
PB1-F2 expression by 2009 H1N1 strain does not increase virulence
Protection against 2009 H1N1 infection by immunization with older strains
Passage in eggs changes influenza receptor specificity
Association between D222G mutation and virulence

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TWiV 62: Persistence of West Nile virus

Vincent Racaniello — Sun, 13 Dec 2009 14:05:47 +0000

Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove

Vincent, Dickson, and Alan discuss STEP HIV-1 vaccine failure caused by the adenovirus vector, presence of West Nile virus in kidneys for years after initial infection, adaptation of the influenza viral RNA polymerase for replication in human cells, and the significance of the D225G change in the influenza HA protein.

Sponsor: Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #62 (47 MB .mp3, 66 minutes)