Hosts: Vincent Racaniello, Rich Condit, and Alan Dove

Vincent, Alan, and Rich review ten compelling virology stories of 2011.

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Click the arrow above to play, or right-click to download TWiV 164 (60 MB .mp3, 99 minutes).

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Ten virology stories of 2011:

1. XMRV, CFS, and prostate cancer (TWiV 119, 123, 136, 150)
2. Influenza H5N1, ferrets, and the NSABB (TWiV 159)
3. The Panic Virus (TWiV 117)
4. Polio eradication (TWiV 127, 149)
5. Viral oncotherapy (TWiV 124, 131, 142, 156)
6. Hepatitis C virus (TWiV 130, 137, 141)
7. Zinc finger nuclease and HIV therapy (TWiV 144)
8. Bacteria help viruses (TWiV 154)
9. Human papillomaviruses (TWiV 126)
10. Combating dengue with Wolbachia (TWiV 115, 147)

Links for this episode:

• Honorable mention: Color me infected (TWiV 115)
• Lo-Alter retraction (PNAS)
• Propose an ASM General Meeting session
• TWiV on Facebook
• Letters read on TWiV 164

Weekly Science Picks

Rich - Fundamentals of Molecular Virology by Nicholas H. Acheson
Alan – Fetch, with Ruff Ruffman
Vincent – Year end reviews at Rule of 6ix and Contagions

Listener Pick of the Week

Garren – Trillion-frame-per-second video
Judi – iBioMagazine
Ricardo – Brain Picking’s 11 best science books of 2011

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, Dickson Despommier, and Alan Dove

The complete TWiV gang discusses the use of Wolbachia to control mosquito-borne infections.

Click the arrow above to play, or right-click to download TWiV 147 (64 MB .mp3, 89 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• miRNAs and colonization by Wolbachia (PNAS)
• Wolbachia blocks dengue, invades caged mosquitos (Nature)
• Establishment of Wolbachia in Aedes populations (Nature)
• Ed Yong on dengue control by Wolbachia
• TWiV on Facebook
• Letters read on TWiV 147

Weekly Science Picks

Alan – Sid the science kid
Dickson – Through the alimentary canal with gun and camera by George S. Chappell
Vincent – Rule of 6ix
Rich – Reality check

Listener Pick of the Week

Liam – Scitable

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Marc Pelletier

Vincent, Alan, Rich and Marc discuss the finding that a limited number of incoming herpesviral genomes can replicate and express in a cell, and controlling viral replication in Aedes aegypti with a Wolbachia symbiont.

Click the arrow above to play, or right click to download TWiV #115 (84 MB .mp3, 117 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Replication and expression of limited numbers of incoming viral genomes
• The brainbow cassette
• Release of Wolbachia infected mosquitoes in Australia (story one, two)
• Journal articles on Wolbachia infection of mosquitoes (Cell, PloS Pathogens)
• Wolbachia discussion on TWiV 61
• TWiV on Facebook
• Letters read on TWiV 115

Weekly Science Picks

Marc – Homebrew bioreactor (photo, movie) – culture bottle and drive, oil-free vacuum pumps
Rich – Logitech Harmony Universal Remote
Alan – H.M.S. Challenger Reports
Vincent – Sequence of the strawberry genome and blog post by lead author

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich revisit ten compelling virology stories of 2010.

Click the arrow above to play, or right click to download TWiV #114 (64 MB .mp3, 88 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Ten virology stories of 2010:

1. XMRV, CFS, and prostate cancer (TWiV 113, 99, 98, 94, 89, 76, 70, 65)
2. The ongoing saga of polio eradication (TWiV 110, 79)
3. Viruses interact with the miRNA/siRNA system (TWiV 108, 72)
4. Endogenous viruses – retro and beyond (TWiV 105, 91, 88, 65)
5. Dengue virus progress and new outbreak (TWiV 111, 95, 82)
6. Colony collapse disorder (TWiV 104)
7. David Baltimore (TWiV 100)
8. Ode to a plaque (TWiV 68)
9. Vaccine contamination with circovirus (TWiV 86, 77, 75)
10. Universal influenza vaccines (TWiV 107)

Weekly Science Picks

Rich – Elementary schoolchildren publish a science paper (original article and editorial with video) – thanks Kathy!
Alan – White-nose syndrome blog
Vincent – Headway, headlines and healthy skepticism

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Ed Fussell, Andrea Leal, and Amy Sargent

The TWiV crew meets with members of the Florida Keys Mosquito Control District at Florida Gulf Coast University to discuss dengue in Florida and how to control it.

Click the arrow above to play, or right-click to download TWiV #111 (76 MB .mp3, 105 minutes). To download, right-click or control-click on the link, then select save as.

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Links for this episode:

• Florida Keys Mosquito Control District
• Prof. Sharon Isern
• Florida Gulf Coast University
• CDC report on dengue in the Florida Keys
• Dengue in Miami
• Mosquito release in the Caymans (Oxitec press release - pdf)
• Concerns about mosquito release
• TWiV on Facebook – photos of TWiV 111
• Letters read on TWiV 111
• Video of this episode – Download .mp4 (136 MB) or .wmv (457 MB) or view below

Weekly Science Picks

Rich – At the Bench, A Laboratory Navigator by Kathy Barker
Alan – DEEP Indonesia Underwater Photo Contest 2010 Winners
Vincent – HHMI resources for early-career scientists

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rosa Maria del Angel, and Ana Lorena Gutiérrez

Vincent visits Mexico City and speaks with Rosa Maria del Angel and Ana Lorena Gutiérrez about virology in Mexico, and their work on dengue and caliciviruses.

Click the arrow above to play, or right-click to download TWiV #109 (58 MB .mp3, 80 minutes). To download, right-click or control-click on the link, then select save as.

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Rosa’s PNAS paper on proteins that bind poliovirus RNA
• Lorena’s papers on influence of proteins that bind poliovirus RNA on tropism and attenuation
• CINVESTAV
• TWiV on Facebook

Weekly Science Picks

Lorena – Caliciviruses by Hansman, Jiang, and Green
Vincent – Insights into dengue virus genome replication by Alcaraz-Estrada, Yocupicio, and del Angel

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich answer listener questions about poliovirus, social media, dengue, influenza, evolution, gel filtration, and much more.

Click the arrow above to play, or right-click to download TWiV #107 (68 MB .mp3, 94 minutes). To download, right-click or control-click on the TWiV #107 link, then select save as.

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• tre recombinase: paper one and two
• Universal influenza vaccines
• Mitochondrial and chlorophast phage-type RNA polymerase in plants
• Protein Data Bank
• Letters read on TWiV 107

Weekly Science Picks

Rich – Protein Synthesis: An epic on the cellular level
Dickson – The Patchwork Mouse by Joseph R. Hixson
Alan – Bill Hammack’s engineering videos
Vincent – Visual Science (thanks, Svetlana)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich consider the end of the influenza H1N1 pandemic, dengue in Florida, vaccinia virus infection in Brazilian monkeys, and viruses in the faecal microbiota.

Click the arrow above to play, or right-click to download TWiV #95 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• WHO declares end of influenza H1N1 pandemic
• CDC’s FluView
• WHO global monitoring of influenza
• Locally acquired dengue in Key West, Florida (MMWR)
• CDC page on dengue
• Vaccinia virus infection in monkeys of the Brazilian Amazon
• Dam site where animals were collected for vaccinia study (Google maps)
• Rich’s article: Whence feral vaccinia?
• Viruses in the faecal microbiota of monozygotic twins and their Mothers (Nature)
• New Yorker article The Treatment (thanks, Jim!)
• Letters read on TWiV 95

Weekly Science Picks

Alan – Families Fighting Flu
Rich – Food, Inc.
Dickson –  Fuel
Vincent – MIT Open Courseware
Michael –  Waiting for Superman and Can Science Feed the World? (Nature)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and Rich Condit

Vincent and Rich talk about how thymic selection of T cells might lead to better control of HIV-1 infection, and a mouse model for severe antibody-induced dengue virus disease.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #82 (59 MB .mp3, 82 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Effect of thymic selection of T-cells on control of AIDS
• Mouse model of antibody-induced severe dengue virus disease
• Natural antibody protects against viral infection
• Kary Mullis idea for fighting infections (thanks, Erik!)
• 40 nm resolution of fluorescence photoactivation localization microscopy (thanks, José)
• Letters read on TWiV 82

Weekly Science Picks

Rich The Mold in Dr. Florey’s Coat: The Story of the Penicillin Miracle by Eric Lax
Vincent Proteopedia (thanks, Erik!)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich discuss ten compelling virology stories of 2009.

Click the arrow above to play, or right-click to download TWiV #64 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Ten virology stories of 2009:

1. Pandemic influenza: Swine-origin H1N1 virus (TWiV 36)
2. XMRV, prostate cancer, and chronic fatigue syndrome (TWiV 50, 55)
3. AIDS vaccine ‘success’ (TWiV 51)
4. Colony collapse disorder (TWiV 46, 49)
5. AIDS-like disease in wild chimps (TWiV 45)
6. Diverse viral community in Antarctic lake (TWiV 58)
7. Polyomavirus seroepidemiology in humans (TWiV 26)
8. Poxvirus threatens UK red squirrels (TWiV 63)
9. Polio spreads from Nigeria (TWiV 29)
10. How mosquitoes survive Dengue virus infection (TWiV 21)

Picture book on viruses for kids (Thanks Soraia!)

Weekly Science Picks
Rich Surely You’re Joking, Mr. Feynman! by Richard P. Feynman, Ralph Leighton, Edward Hutchings, and Albert R. Hibbs
Alan Spaceweather.com
Vincent The Art and Politics of Science by Harold Varmus

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.