Hosts: Vincent Racaniello and Kathy Spindler Guests: Michael Imperiale, Adam Lauring, and Akira Ono Vincent visits the University of Michigan where he and Kathy speak with Michael, Adam, and Akira about polyomaviruses, virus evolution, and virus assembly, on the occasion of naming the department of Microbiology & Immunology a Milestones in Microbiology site. Click arrow to play […]


TWiV 348: Chicken shift

August 2, 2015

Hosts: Vincent Racaniello and Rich Condit Vincent and Rich discuss fruit fly viruses, one year without polio in Nigeria, and a permissive Marek’s disease viral vaccine that allows transmission of virulent viruses. Click arrow to play Download TWiV 348 (77 MB .mp3, 106 min) Subscribe (free): iTunes, RSS, email Links for this episode Virology tenure-track position at NCI (pdf) 9:30 ASM Agar Art Contest 11:00 Nigeria on brink of polio […]


TWiV 335: Ebola lite

May 3, 2015

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVumvirate discusses a whole Ebolavirus vaccine that protects primates, the finding that Ebolavirus is not undergoing rapid evolution, and a proposal to increase the pool of life science researchers by cutting money and time from grants. Click arrow to play Download TWiV 335 (79 MB .mp3, 110 min) Subscribe […]


Host: Vincent Racaniello Guests: Seth Bordenstein, James Crowe, and Mark Denison Vincent visits Vanderbilt University and meets up with Seth, Jim, and Mark to talk about their work on a virus of Wolbachia, anti-viral antibodies, and coronaviruses. Click arrow to play Download TWiV 332 (70 MB .mp3, 97 min) Subscribe (free): iTunes, RSS, email Links for this episode SARS-CoV error correction (PLoS […]


Hosts: Vincent Racaniello and Rich Condit Guest: Eugene Koonin Vincent and Rich meet up with Eugene Koonin to talk about the central role of viruses in the evolution of all life. Click arrow to play Download TWiV 275 (94 MB .mp3, 130 min) Subscribe (free): iTunes, RSS, email Links for this episode Virocentric view of evolution (Curr Op Virol) Proposed order Megavirales (Arch […]


TWiV 242: I want my MMTV

July 21, 2013

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The complete TWiV team talks about how two different viruses shape the evolution of an essential housekeeping protein. Click arrow to play Download TWiV 242 (67 MB .mp3, 93 min) Subscribe (free): iTunes, RSS, email Links for this episode: Dual virus-host arms race (PLoS Biology) Dual virus-receptor […]

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Hosts: Vincent Racaniello and Rich Condit Guest: Michael Emerman Vincent and Rich recorded this episode at the Fred Hutchinson Cancer Research Center in Seattle, WA, where they met up with Michael to talk about his work on the molecular and evolutionary basis of HIV replication and pathogenesis. Click arrow to play Download TWiV 237 (59 MB .mp3, 81 […]

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Hosts: Vincent Racaniello and Kathy Spindler Guests: Nels Elde and Tom Shenk Vincent and Kathy recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Nels and Tom about their work on the evolution of virus-host conflict and how viruses influence the cell […]


Hosts: Vincent Racaniello and Harmit Malik Vincent is joined by special guest Harmit Malik to discuss his work on the evolution of genetic conflict. Click the arrow above to play, or right-click to download TWiV 205 (74 MB .mp3, 103 minutes). Subscribe to TWiV (free) in iTunes, by the RSS feed, by email, or listen on your mobile […]


Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Vincent, Alan, Rich, and Kathy review fatal avian influenza virus in harbor seals, and poxvirus deployment of genomic accordions to counter antiviral defenses. Click the arrow above to play, or right-click to download TWiV 198 (71 MB .mp3, 99 minutes). There once was a virus named pox […]