Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Michael Walsh

Michael and the TWiV team review epidemiology basics, including fatality ratios.

Click the arrow above to play, or right-click to download TWiV 169 (64 MB .mp3, 152 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Michael’s blog and podcast
• Epidemiology literature critique (PowerPoint)
• Seven mistakes in epidemiology (ETE)
• Snow cholera map
• TWiV on Facebook
• Letters read on TWiV 169

Weekly Science Picks

Michael – Love my epi
Dickson – Bacteria array detects arsenic
Rich – Dunning-Kruger effect
Alan – Environmental Economics
Vincent – Don’t censor influenza research

Listener Pick of the Week

Simon – The Great Mortality by John Kelly

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Welkin Johnson

Welkin joins the TWiV team for a discussion of HIV prophlaxis using vectored antibodies, and the influenza H5N1 virus studies in ferrets that were not redacted.

Click the arrow above to play, or right-click to download TWiV 168 (59 MB .mp3, 98 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Vectored HIV immunoprophylaxis (Nature)
• Vectored immunoprophylaxis – the Movie (YouTube)
• Adeno-associated virus (Wikipedia)
• In vitro evolution of H5N1 towards human receptor specificity (Virology)
• Endogenous viral genes non-essential in chicken (Nature)
• Rates of HIV transmission per coital act (J Inf Dis)
• TWiV on Facebook
• Letters read on TWiV 168

Weekly Science Picks

Welkin – Virtual PI (Nature)
Dickson – Drain the Ocean
Rich – Nova: To the Moon
Alan - Robert Falcon Scott on Twitter and the Terra Nova expedition
Vincent – Hello, Mr. Chips (I, Cringely)

Listener Pick of the Week

Charlotte – And the Band Played On

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

The complete TWiVome deconstructs the movie Contagion.

Click the arrow above to play, or right-click to download TWiV 167 (53 MB .mp3, 88  minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• R0 explained (pdf)
• Hendra and Nipah encephalitis (CDC)
• Contagion (IMdB)
• TWiV on Facebook
• Letters read on TWiV 167

Weekly Science Picks

Dickson – Guinea Pig Doctors by Jon Franklin
Rich – Learn to appreciate technology and Everythings amazing and nobodys happy (YouTube)
Alan – JD Hooker slide collection
Vincent – iTunes U app and iBooks Author

Listener Pick of the Week

Judi – Makers of Many Things by Eva March Tappan

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Alan Dove

Vincent, Alan, and Rich review ten compelling virology stories of 2011.

Please help us by taking our listener survey.

Click the arrow above to play, or right-click to download TWiV 164 (60 MB .mp3, 99 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Ten virology stories of 2011:

1. XMRV, CFS, and prostate cancer (TWiV 119, 123, 136, 150)
2. Influenza H5N1, ferrets, and the NSABB (TWiV 159)
3. The Panic Virus (TWiV 117)
4. Polio eradication (TWiV 127, 149)
5. Viral oncotherapy (TWiV 124, 131, 142, 156)
6. Hepatitis C virus (TWiV 130, 137, 141)
7. Zinc finger nuclease and HIV therapy (TWiV 144)
8. Bacteria help viruses (TWiV 154)
9. Human papillomaviruses (TWiV 126)
10. Combating dengue with Wolbachia (TWiV 115, 147)

Links for this episode:

• Honorable mention: Color me infected (TWiV 115)
• Lo-Alter retraction (PNAS)
• Propose an ASM General Meeting session
• TWiV on Facebook
• Letters read on TWiV 164

Weekly Science Picks

Rich - Fundamentals of Molecular Virology by Nicholas H. Acheson
Alan – Fetch, with Ruff Ruffman
Vincent – Year end reviews at Rule of 6ix and Contagions

Listener Pick of the Week

Garren – Trillion-frame-per-second video
Judi – iBioMagazine
Ricardo – Brain Picking’s 11 best science books of 2011

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review concern over an influenza H5N1 transmission experiment, and a new host defense protein against RNA viruses.

Please help us by taking our listener survey.

Click the arrow above to play, or right-click to download TWiV 159 (48 MB .mp3, 80 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Concern over H5N1 transmission experiment (CIDRAP)
• Information on NSABB
• Enserink’s overstated story (Science)
• New cell defense protein against RNA viruses (Nature Chem Biol)
• Uta Schwedler obituary (jpg)
• TWiV on Facebook
• Letters read on TWiV 159

Weekly Science Picks

Rich – Livescribe Smartpen
Alan – Royal Society journal archive
Vincent - Chronic fatigue syndrome and the CDC by Dave Tuller

Listener Pick of the Week

Judi – Top 7 in Microbiology

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Dickson Despommier

Vincent, Dickson, and Rich meant to do an all-email episode, but first they review results of the Blood XMRV Scientific Research Working Group, and partial retraction of the paper associating XMRV with chronic fatigue syndrome.

With this episode TWiV is three years old.

Click the arrow above to play, or right-click to download TWiV 150 (56 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Partial retraction (Science)
• Failure to confirm (Science)
• False positive (Science)
• Why a partial retraction? (Retraction Watch)
• TWiV on Facebook
• Letters read on TWiV 150

Weekly Science Picks

Dickson – The Tree of Life
Vincent – When do you fact-check article content with sources? (take as directed)
Rich – io9

Listener Pick of the Week

Luis – NIH videocasting and podcasting

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Alan Dove and Rich Condit

Alan and Rich tackle the discovery of bacteriophages, and treating influenza by calming the cytokine storm.

Click the arrow above to play, or right-click to download TWiV 145 (63 MB .mp3, 87 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Twort on the nature of ultra-microscopic viruses (Lancet)
• Who discovered bacteriophage? (pdf, Bact Rev)
• Calming cytokine storm to treat influenza (PNAS)
• TWiV on Facebook
• Letters read on TWiV 145

Weekly Science Picks

Alan – AT&T Tech Channel
Rich – Smallpox and its eradication (pdf)

Listener Pick of the Week

Asif – Science Photo Library

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, Julie Overbaugh, and Stacey Schultz-Cherry

Vincent, Rich, Julie and Stacey recorded TWiV at the 30th Annual Meeting of the American Society for Virology in Minneapolis, where they discussed the role of neutralizing antibodies in protection against HIV-1 infection, and astroviruses, agents of gastroenteritis.

Click the arrow above to play, or right-click to download TWiV 143 (48 MB .mp3, 66 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• HIV-1 neutralizing antibodies and risk of infant infection (J Virol)
• Astrovirus increases epithelial barrier (J Virol)
• Virology special reviews issue (open access)
• Don Ganem interrupted by fire alarm at ASV (YouTube)
• History of structural virology
• ASV 2011 at Minneapolis
• Photographs of TWiV at ASV
• Photographs of ASV 2011
• TWiV on Facebook
• Letters read on TWiV 143

Weekly Science Picks

Rich – Iter – building a fusion reactor
Vincent – American girls sweep at Google science fair (NY Times)

Listener Pick of the Week

Jing – Bees by Rudolph Steiner

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Michael Katze, Michael Gale, Deborah Fuller, and Shawn Iadonato

A conversation about careers in virology, systems biology, innate immunity, and antiviral research recorded at the University of Washington in Seattle.

Click the arrow above to play, or right click to download TWiV #121 (65 MB .mp3, 90 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• A systems biology approach to infectious disease research (mBio)
• Infectious Curiosity (thanks, Gopal!)
• Astronomy Cast (thanks, Jacob!)
• The Journal of Negative Results (thanks, Patricia!)
• Scientist Solutions (thanks, Patricia!)
• Bacteriophage as antibacterial solution (thanks, Peter!)
• TWiV on Facebook
• Letters read on TWiV 121
• Video of this episode –  view below or download .mp4 (1 GB)

Weekly Science Picks

Michael K – Pasteur Museum
Deborah – Undaunted Courage by Stephen Ambros
Michael G – The Eighth Day of Creation by Horace Freeland Judson
Vincent – The Emperor of All Maladies by Siddhartha Mukherjee

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich review an adenovirus-based vaccine strategy against drug addiction, a field trial of RNAi to prevent Israeli acute paralysis virus infection in honeybees, and suppression of avian influenza transmission in transgenic chickens.

Click the arrow above to play, or right click to download TWiV #116 (64 MB .mp3, 89 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Cocaine analog coupled to disrupted adenovirus
• Field application of RNAi in honeybees
• Suppression of avian influenza transmission in GM chickens (EurekAlert)
• Phage tailspike protein therapy
• Use of phage lysins to treat bacterial infections (one and two)
• Cell to cell spread of viruses (review and inhibition by tetherin)
• Flock house virus replication organelle (thanks Brett!)
• TWiV on Facebook
• Letters read on TWiV 116

Weekly Science Picks

Dickson – Brian Deer’s investigation of Andrew Wakefield
Rich – Photographic periodic table of the elements
Alan – Year of the bat (site one and site two)
Vincent – EteRNA (NY Times article)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.