Hosts: Vincent Racaniello, Rich Condit, Dickson Despommier, and Alan Dove

The complete TWiV gang discusses the use of Wolbachia to control mosquito-borne infections.

Click the arrow above to play, or right-click to download TWiV 147 (64 MB .mp3, 89 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• miRNAs and colonization by Wolbachia (PNAS)
• Wolbachia blocks dengue, invades caged mosquitos (Nature)
• Establishment of Wolbachia in Aedes populations (Nature)
• Ed Yong on dengue control by Wolbachia
• TWiV on Facebook
• Letters read on TWiV 147

Weekly Science Picks

Alan – Sid the science kid
Dickson – Through the alimentary canal with gun and camera by George S. Chappell
Vincent – Rule of 6ix
Rich – Reality check

Listener Pick of the Week

Liam – Scitable

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Marc Pelletier

Vincent, Alan, Rich and Marc discuss the finding that a limited number of incoming herpesviral genomes can replicate and express in a cell, and controlling viral replication in Aedes aegypti with a Wolbachia symbiont.

Click the arrow above to play, or right click to download TWiV #115 (84 MB .mp3, 117 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Replication and expression of limited numbers of incoming viral genomes
• The brainbow cassette
• Release of Wolbachia infected mosquitoes in Australia (story one, two)
• Journal articles on Wolbachia infection of mosquitoes (Cell, PloS Pathogens)
• Wolbachia discussion on TWiV 61
• TWiV on Facebook
• Letters read on TWiV 115

Weekly Science Picks

Marc – Homebrew bioreactor (photo, movie) – culture bottle and drive, oil-free vacuum pumps
Rich – Logitech Harmony Universal Remote
Alan – H.M.S. Challenger Reports
Vincent – Sequence of the strawberry genome and blog post by lead author

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Ed Fussell, Andrea Leal, and Amy Sargent

The TWiV crew meets with members of the Florida Keys Mosquito Control District at Florida Gulf Coast University to discuss dengue in Florida and how to control it.

Click the arrow above to play, or right-click to download TWiV #111 (76 MB .mp3, 105 minutes). To download, right-click or control-click on the link, then select save as.

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Florida Keys Mosquito Control District
• Prof. Sharon Isern
• Florida Gulf Coast University
• CDC report on dengue in the Florida Keys
• Dengue in Miami
• Mosquito release in the Caymans (Oxitec press release - pdf)
• Concerns about mosquito release
• TWiV on Facebook – photos of TWiV 111
• Letters read on TWiV 111
• Video of this episode – Download .mp4 (136 MB) or .wmv (457 MB) or view below

Weekly Science Picks

Rich – At the Bench, A Laboratory Navigator by Kathy Barker
Alan – DEEP Indonesia Underwater Photo Contest 2010 Winners
Vincent – HHMI resources for early-career scientists

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit

Vincent, Dickson, and Rich discuss multipotent progenitor bone marrow cells as a reservoir of HIV-1, integration of HHV-6 into telomeres, and dispersal of West Nile virus across the US by mosquitoes.

This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #73 (63 MB .mp3, 87 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• HIV-1 infects multipotent progenitor cells
• HHV-6 genome integrates into telomeres
• A role for mosquito-mediated dispersal of West Nile virus across the US
• Using tobacco  mosaic virus to produce synthetic photovoltaic cells (thanks Nissin!)
• Animation of HIV replication cycle (thanks Ilya!)
• Can computer viruses evolve? (thanks Norman!)
• Mumps outbreak in Israel (one and two) (thanks Ariel!)
• Bocavirus infections in children (thanks Tyler!)

Weekly Science Picks

Dickson Whole-Genome Sequencing in a Patient with Charcot–Marie–Tooth Neuropathy (NEJM and NY Times)
Rich Invisible Frontiers: The Race to Synthesize a Human Gene by Stephen Hall
Vincent Conference on Retroviruses and Opportunistic Infections –  videocasts

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich discuss ten compelling virology stories of 2009.

Click the arrow above to play, or right-click to download TWiV #64 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Ten virology stories of 2009:

1. Pandemic influenza: Swine-origin H1N1 virus (TWiV 36)
2. XMRV, prostate cancer, and chronic fatigue syndrome (TWiV 50, 55)
3. AIDS vaccine ‘success’ (TWiV 51)
4. Colony collapse disorder (TWiV 46, 49)
5. AIDS-like disease in wild chimps (TWiV 45)
6. Diverse viral community in Antarctic lake (TWiV 58)
7. Polyomavirus seroepidemiology in humans (TWiV 26)
8. Poxvirus threatens UK red squirrels (TWiV 63)
9. Polio spreads from Nigeria (TWiV 29)
10. How mosquitoes survive Dengue virus infection (TWiV 21)

Picture book on viruses for kids (Thanks Soraia!)

Weekly Science Picks
Rich Surely You’re Joking, Mr. Feynman! by Richard P. Feynman, Ralph Leighton, Edward Hutchings, and Albert R. Hibbs
Alan Spaceweather.com
Vincent The Art and Politics of Science by Harold Varmus

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Dick Despommier, and Hamish Young

Vincent, Alan, Dick, and Hamish Young discuss the 2009 influenza pandemic, first 2009 H1N1 vaccine, hunting mosquitoes with midges, vaccine-associated polio in India, and adenoviruses.

Sponsor:  Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #36 (64 MB .mp3, 93 minutes)

Links for this episode:

Weekly Science Picks
Dick The World’s Water by Peter H. Gleick
Hamish Guns, Germs, and Steel by Jared Diamond; Complications by Atul Gawande
Alan Eurekalert
Vincent Respectful Insolence

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Subscribe to TWiV in iTunes, by the RSS feed, or by email

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich Condit converse about induction of polyomavirus replication in multiple sclerosis patients treated with the MS drug Tysabri, the extent of human polyomavirus infection, selection of influenza vaccines for the 2009-10 season, cowpox virus transmission from animals to humans, vaccinia-like virus infecting humans and cattle in Brasil, and poxviruses.

Click the arrow above to play, or right-click to download TWiV #26 (52 MB .mp3, 75 minutes)

Links for this episode:

• JC virus, Tysabri, PML, and mefloquine at virology blog
• Seroepidemiology of polyomaviruses in human
• Next season’s influenza virus vaccines and how they are selected
• Cell-culture propagated smallpox vaccine
• Cowpox tranmission from rats to humans (Germany and France) and from cats to humans in Italy
• Vaccinia-like virus infecting cows and humans in Brasil
• When good vaccines go wild (review)
• Mosquito Map (thanks Duncan)
• Pfeiffer & Kirkegaard paper on quasispecies and virulence in mice

Science blog of the week: Coevolvers by Devin Drown
Science podcast pick of the week: QuackCast
Science book of the week: Listen to the Music: The Life of Hilary Koprowski by Roger Vaughan

Send your virology questions and comments to twiv@twiv.tv

Subscribe to TWiV in iTunes, by the RSS feed, or by email

We recorded episode 1 of TWiV on 12 September 2008, and again on 19 September. Sorry for the delay in posting, we had post-production problems. Download the netcast below. We’ll post the iTunes link as soon as it is accepted by Apple.

Hosts: Vincent Racaniello and Dickson Despommier.

Click the arrow above to play, or right-click to download TWiV #1 (41.8 MB .mp3 file)

Links for this episode:

• Buy “West Nile Story” by Dickson Despommier.
• ProMed Mail. The global reporting system for outbreaks of emerging infectious disease.
• PubMed. A service of the National Library of Medicine, includes over 14 million citations for biomedical articles back to the 1950s.
• West Nile page at Centers for Disease Control and Prevention. Great maps of where the virus has been found.

Episode transcript (download pdf)

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