Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing. Click arrow to play Download TWiV 328 (67 MB .mp3, 92 min) Subscribe (free): iTunes, RSS, email Links for this episode Viral polymerase binds Prp8 to inhibit mRNA splicing (PLoS Path) Prp8 protein of the […]


Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The complete TWiV team reviews evidence for sensing of herpesviral DNA in the nucleus by the cell protein IFI16. Click arrow to play Download TWiV 269 (74 MB .mp3, 102 min) Subscribe (free): iTunes, RSS, email Links for this episode IFI16 is a nuclear pathogen sensor (Cell Host Micr) Nuclear IFI16 […]


Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich revisit circovirus contamination of Rotarix, then discuss poxvirus-like replication of mimivirus in the cell cytoplasm, and whether seasonal influenza immunization increases the risk of infection with the 2009 H1N1 pandemic virus. This episode is sponsored by Data Robotics Inc. Use the promotion code […]