Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich explore a novel bunyavirus isolated in China, the recent polio outbreak in Republic of the Congo, and cell to cell transmission of a retrovirus by biofilm-like extracellular assemblies.

Click the arrow above to play, or right-click to download TWiV #127 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Novel bunyavirus isolated in China (NEJM)
• Bunyavirus page at ViralZone
• Polio outbreak, Republic of the Congo (MMWR)
• Poliovirus isolation from Republic of the Congo polio outbreak (Eurosurveillance)
• HTLV-1 transmission by biofilm-like extracellular assemblies (Nature Medicine)
• TWiV on Facebook
• Letters read on TWiV 127

Weekly Science Picks

Rich – Should smallpox be destroyed? (Emerging Infectious Diseases)
Alan – Zoology of the Beagle images
Vincent – Vaccines and Your Child by Paul Offit and Charlotte Moser

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich revisit ten compelling virology stories of 2010.

Click the arrow above to play, or right click to download TWiV #114 (64 MB .mp3, 88 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Ten virology stories of 2010:

1. XMRV, CFS, and prostate cancer (TWiV 113, 99, 98, 94, 89, 76, 70, 65)
2. The ongoing saga of polio eradication (TWiV 110, 79)
3. Viruses interact with the miRNA/siRNA system (TWiV 108, 72)
4. Endogenous viruses – retro and beyond (TWiV 105, 91, 88, 65)
5. Dengue virus progress and new outbreak (TWiV 111, 95, 82)
6. Colony collapse disorder (TWiV 104)
7. David Baltimore (TWiV 100)
8. Ode to a plaque (TWiV 68)
9. Vaccine contamination with circovirus (TWiV 86, 77, 75)
10. Universal influenza vaccines (TWiV 107)

Weekly Science Picks

Rich – Elementary schoolchildren publish a science paper (original article and editorial with video) – thanks Kathy!
Alan – White-nose syndrome blog
Vincent – Headway, headlines and healthy skepticism

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Alan, Rich, and Dickson discuss bacteria that can utilize arsenic in place of phosphorus, the passing of Frank Fenner, polio outbreak in The Congo, solving criminal cases of HIV transmission, and classifying viruses by capsid structure.

Click the arrow above to play, or right-click to download TWiV #110 (68 MB .mp3, 93 minutes). To download, right-click or control-click on the link, then select save as.

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Bacteria that utilize arsenic (Ed Yong’s view)
• Frank Fenner passes away
• Smallpox and its eradication – the ‘red book’ (pdf)
• Polio outbreak in The Congo (virus isolation)
• Solving criminal cases with HIV evolution (press release)
• Definition of paraphyly
• Order to the viral universe
• International Committee on Taxonomy of Viruses (ICTV)
• TWiV on Facebook
• Letters read on TWiV 110

Weekly Science Picks

Dickson – CDC’s West Nile virus case count for 2010
Rich – The red bees of Red Hook
Alan – Arsenic-based life at XKCD
Vincent – PLoS iPad app

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich answer listener questions about lab procedures, prokaryotes, endogenous retroviruses, the iPad and teaching, prions, mimivirus, splitting water with viruses, and the polio outbreak in Tajikistan.

Click the arrow above to play, or right-click to download TWiV #93 (76 MB .mp3, 105 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Biomedical Advanced Research and Development Authority (BARDA)
• SIGA responds to BARDA request for smallpox antiviral
• BARDA contract for filovirus vaccine
• What is a Ph.D? (pdf)
• HHMI resources for early career scientists
• Pace article on abandoning prokaryote (Nature)
• Three domains of life (Forterre article)
• Mechanoenzymatic cleavage of Von Willebrand’s factor (Science)
• Splitting water with viruses
• WHO coverage on Tajikstan polio outbreak
• Wild type polio infection in immunized Indian children (JID)
• Letters read on TWiV 93

Weekly Science Picks

Alan – Southern Fried Science
Rich – Tree of Life web project
Vincent – Dickson Despommier at Big Think

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, Karla Kirkegaard, and Marilyn Roosinck

Vincent, Rich, Karla, and Marilyn recorded TWiV at the 29th Annual Meeting of the American Society for Virology in Bozeman, where they discussed plant viruses and how they make plants resistant to adverse conditions, and identification of dominant negative drug targets.

Click the arrow above to play, or right-click to download TWiV #92 (42 MB .mp3, 57 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Lifestyles of plant viruses
• Using pyrosequencing to understand virus ecology
• A virus in a fungus in a plant
• Trans-dominant inhibition of RNA viral replication
• Resistance is futile
• Announcement of TWiV at ASV (pdf)
• Photographs of TWiV at ASV
• Letters read on TWiV 92

Weekly Science Picks

Marilyn – Viruses in the faecal microbiota of monozygotic twins and their mothers (Nature)
Rich – The Known Universe by the American Museum of Natural History
Vincent – The Red Queen by Matt Ridley (thanks, Jesper!)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and Alan Dove

Vincent and Alan converse about making published science accessible to everyone, global eradication of poliomyelitis, and whether a plant virus can cause disease in humans.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #79 (51 MB .mp3, 71 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• Making published science accessible to everyone (Nature News)
• Federal Research Public Access Act
• Is disease eradication a waste of money?
• Do we have an ethical obligation to eradicate polio?
• Signs of progress in polio eradication (NY Times)
• Polio eradication: Harder than it looks (Fortner)
• Gates rethinks his war on polio (WSJ)
• Asymptomatic wild-type poliovirus infection in immune children (J Inf Dis)
• Can a plant virus cause disease in humans? (PLoS One)
• Replication of tomato spotted wilt virus in HeLa cells (PNAS)
• Glycine detected in comet (thanks Vincent!)

Weekly Science Picks

Alan Data.gov
Vincent foldit

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich discuss ten compelling virology stories of 2009.

Click the arrow above to play, or right-click to download TWiV #64 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Ten virology stories of 2009:

1. Pandemic influenza: Swine-origin H1N1 virus (TWiV 36)
2. XMRV, prostate cancer, and chronic fatigue syndrome (TWiV 50, 55)
3. AIDS vaccine ‘success’ (TWiV 51)
4. Colony collapse disorder (TWiV 46, 49)
5. AIDS-like disease in wild chimps (TWiV 45)
6. Diverse viral community in Antarctic lake (TWiV 58)
7. Polyomavirus seroepidemiology in humans (TWiV 26)
8. Poxvirus threatens UK red squirrels (TWiV 63)
9. Polio spreads from Nigeria (TWiV 29)
10. How mosquitoes survive Dengue virus infection (TWiV 21)

Picture book on viruses for kids (Thanks Soraia!)

Weekly Science Picks
Rich Surely You’re Joking, Mr. Feynman! by Richard P. Feynman, Ralph Leighton, Edward Hutchings, and Albert R. Hibbs
Alan Spaceweather.com
Vincent The Art and Politics of Science by Harold Varmus

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dick Despommier, Alan Dove, and Jennifer Drahos

Vincent, Dick, Alan, and Jennifer Drahos tackle the Hendra virus disease outbreak in Australia, AIDS-like disease in wild chimps, return of polio type 2 in Nigeria, the influenza pandemic wave, and rabies in three countries.

Sponsor:  Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #45 (59 MB .mp3, 86 minutes)

Links for this episode:

Weekly Science Picks
Jennifer Art of Science 2009
Vincent Nobel Intent
Dick Diversity of Life by EO Wilson
Alan MediaWiki (install tips)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast

Subscribe to TWiV in iTunes, by the RSS feed, or by email

Hosts: Vincent Racaniello, Alan Dove, and Raul Rabadan

Vincent, Alan, and Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome sequence analysis of influenza H1N1 viruses.

Sponsor:  Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #32 (51 MB .mp3, 73 minutes)

Links for this episode:

TWiV will be live at the ASM General Meeting in Philadelphia on Tuesday, May 19, 2:00 PM, Press Room 203A. Video will be streamed live at this location.

Weekly Science Picks
Alan The Franklin Institute Science Museum in Philadelphia
Vincent Pi Cubed for iPhone/iPod Touch (Sunset Lake Software, $9.99)
Raul Science and New England Journal articles on H1N1 influenza

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Subscribe to TWiV in iTunes, by the RSS feed, or by email

Hosts: Vincent Racaniello, Dick Despommier, and Alan Dove

Vincent, Dick, and Alan talk about insect and human dengue virus host proteins, equine vaccine for WNV and EEEV, return of swine flu to humans, spread of polio in Africa, and listener email.

Sponsor:  Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #29 (49 MB .mp3,  70 minutes)

Links for this episode:

Science blog of the week: Science-based medicine
Science podcast pick of the week: WNYC’s Radio Lab
Science book of the week: Flu by Gina Kolata

Send your virology questions and comments to twiv@twiv.tv

Subscribe to TWiV in iTunes, by the RSS feed, or by email