Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich are very enthusiastic about two studies that show how gut bacteria help viral invaders.

Click the arrow above to play, or right-click to download TWiV 154 (46 MB .mp3, 77 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• TWiV154 transcript (pdf)
• Retrovirus transmission dependent on commensal microbiota (Science)
• Intestinal microbiota promote enteric virus replication (Science)
• TWiV 3D timeline (9 MB .mv4 – thanks, Ricardo)
• Faleye’s photos at VirusTalk
• TWiV on Facebook
• Letters read on TWiV 154

Weekly Science Picks

Alan – SciWriteLabs
Vincent – Take as directed

Listener Pick of the Week

Tony – Introduction to AI online course

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, Mark Pallansch, and Trine Tsouderos

Vincent, Rich, Mark, and Trine discuss science and medicine in journalism and the eradication of poliovirus at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

Click the arrow above to play, or right-click to download TWiV 149 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• ICAAC 2011
• Recent Chicago Tribune articles by Trine
• Polio eradication initiative
• CDC 101: Zombie Apocalypse
• TWiV on Facebook
• Letters read on TWiV 149
• Video of this episode below

Weekly Science Picks

Rich – Parachute use to prevent death (Brit Med J)
Vincent – Ian Lipkin’s Op-Ed on Contagion and a review of the movie (both NY Times)

Listener Pick of the Week

Michael – Bacteria billboard for Contagion (YouTube)

This episdode of TWiV is sponsored by Wiley-Blackwell, the leading scientific publisher of books, scholarly journals, major reference works and databases. This month they are offering 25%-off all Microbiology and Virology books. To take advantage of this offer go to www.wiley.com/go/microbeworld.

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich explore a novel bunyavirus isolated in China, the recent polio outbreak in Republic of the Congo, and cell to cell transmission of a retrovirus by biofilm-like extracellular assemblies.

Click the arrow above to play, or right-click to download TWiV #127 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Novel bunyavirus isolated in China (NEJM)
• Bunyavirus page at ViralZone
• Polio outbreak, Republic of the Congo (MMWR)
• Poliovirus isolation from Republic of the Congo polio outbreak (Eurosurveillance)
• HTLV-1 transmission by biofilm-like extracellular assemblies (Nature Medicine)
• TWiV on Facebook
• Letters read on TWiV 127

Weekly Science Picks

Rich – Should smallpox be destroyed? (Emerging Infectious Diseases)
Alan – Zoology of the Beagle images
Vincent – Vaccines and Your Child by Paul Offit and Charlotte Moser

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich answer listener questions about poliovirus, social media, dengue, influenza, evolution, gel filtration, and much more.

Click the arrow above to play, or right-click to download TWiV #107 (68 MB .mp3, 94 minutes). To download, right-click or control-click on the TWiV #107 link, then select save as.

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• tre recombinase: paper one and two
• Universal influenza vaccines
• Mitochondrial and chlorophast phage-type RNA polymerase in plants
• Protein Data Bank
• Letters read on TWiV 107

Weekly Science Picks

Rich – Protein Synthesis: An epic on the cellular level
Dickson – The Patchwork Mouse by Joseph R. Hixson
Alan – Bill Hammack’s engineering videos
Vincent – Visual Science (thanks, Svetlana)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and David Baltimore

Vincent, Alan, and Rich celebrate the 100th episode of TWiV by talking about viruses with Nobel Laureate David Baltimore.

Click the arrow above to play, or right-click to download TWiV #100 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• David’s early papers on poliovirus and mengovirus RNA synthesis
• Reverse transcriptase found by Baltimore and Temin (pdfs)
• Nobel Prize in Physiology or Medicine 1975
• David fishing (Picasa web album)
• The David Baltimore asteroid belt
• Cedric’s essay The ‘Death’ of a Virus (pdf)
• Letters read on TWiV 100

Weekly Science Picks

Alan – TimeTree
Rich – The neurons that shaped civilization
Vincent – Ahead of the Curve: David Baltimore’s Life in Science by Shane Crotty

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Click the arrow above to play, or right-click to download TWiV #98 (58 MB .mp3, 80 minutes)

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Links for this episode:

• MLV-related sequences in blood of CFS patients (commentary)
• Laboratory inventories for poliovirus containment
• Viral batteries for the military (abstract) – also see TWiV 28
• Human rabies, Kentucky/Indiana, 2009
• Letters read on TWiV 98

Weekly Science Picks

Alan – NCBI ROFL
Rich – The Great Bridge by David McCullough
Vincent – Dr. Rous’ Prize-Winning Chicken

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Peter Sarnow, and Bert Semler

During a trip to California, Vincent visited Peter Sarnow and Bert Semler and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication.

Click the arrow above to play, or right-click to download TWiV #97 (66 MB .mp3, 91 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Eukaryotic mRNAs that might contain an IRES (PNAS)
• Modulation of HCV RNA abundance by a liver-specific microRNA (Science)
• Viral small RNAs (PLoS Pathogens)
• Bridging IRES elements to the translation apparatus (Biochim Biophys Acta)
• A nucleo-cytoplasmic SR protein functions in viral IRES mediated translation (EMBO J)
• Nuclear vs cytoplasmic routes to IRES mediated translation (Trends in Microbiology)
• Letter read on TWiV 97

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, Karla Kirkegaard, and Marilyn Roosinck

Vincent, Rich, Karla, and Marilyn recorded TWiV at the 29th Annual Meeting of the American Society for Virology in Bozeman, where they discussed plant viruses and how they make plants resistant to adverse conditions, and identification of dominant negative drug targets.

Click the arrow above to play, or right-click to download TWiV #92 (42 MB .mp3, 57 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Lifestyles of plant viruses
• Using pyrosequencing to understand virus ecology
• A virus in a fungus in a plant
• Trans-dominant inhibition of RNA viral replication
• Resistance is futile
• Announcement of TWiV at ASV (pdf)
• Photographs of TWiV at ASV
• Letters read on TWiV 92

Weekly Science Picks

Marilyn – Viruses in the faecal microbiota of monozygotic twins and their mothers (Nature)
Rich – The Known Universe by the American Museum of Natural History
Vincent – The Red Queen by Matt Ridley (thanks, Jesper!)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and Alan Dove

Vincent and Alan converse about making published science accessible to everyone, global eradication of poliomyelitis, and whether a plant virus can cause disease in humans.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #79 (51 MB .mp3, 71 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• Making published science accessible to everyone (Nature News)
• Federal Research Public Access Act
• Is disease eradication a waste of money?
• Do we have an ethical obligation to eradicate polio?
• Signs of progress in polio eradication (NY Times)
• Polio eradication: Harder than it looks (Fortner)
• Gates rethinks his war on polio (WSJ)
• Asymptomatic wild-type poliovirus infection in immune children (J Inf Dis)
• Can a plant virus cause disease in humans? (PLoS One)
• Replication of tomato spotted wilt virus in HeLa cells (PNAS)
• Glycine detected in comet (thanks Vincent!)

Weekly Science Picks

Alan Data.gov
Vincent foldit

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich discuss ten compelling virology stories of 2009.

Click the arrow above to play, or right-click to download TWiV #64 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Ten virology stories of 2009:

1. Pandemic influenza: Swine-origin H1N1 virus (TWiV 36)
2. XMRV, prostate cancer, and chronic fatigue syndrome (TWiV 50, 55)
3. AIDS vaccine ‘success’ (TWiV 51)
4. Colony collapse disorder (TWiV 46, 49)
5. AIDS-like disease in wild chimps (TWiV 45)
6. Diverse viral community in Antarctic lake (TWiV 58)
7. Polyomavirus seroepidemiology in humans (TWiV 26)
8. Poxvirus threatens UK red squirrels (TWiV 63)
9. Polio spreads from Nigeria (TWiV 29)
10. How mosquitoes survive Dengue virus infection (TWiV 21)

Picture book on viruses for kids (Thanks Soraia!)

Weekly Science Picks
Rich Surely You’re Joking, Mr. Feynman! by Richard P. Feynman, Ralph Leighton, Edward Hutchings, and Albert R. Hibbs
Alan Spaceweather.com
Vincent The Art and Politics of Science by Harold Varmus

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.