Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan review the 100 year old finding by Peyton Rous of a transmissible sarcoma of chickens, a discovery that ushered in the era of tumor virology.

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Click the arrow above to play, or right-click to download TWiV 163 (61 MB .mp3, 102 minutes).

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Links for this episode:

• Transmissible sarcoma of the fowl (J Exp Med)
• Sarcoma of fowl transmissible by agent separable from tumor cells (J Exp Med)
• 100 years of Rous sarcoma virus (J Exp Med)
• Early history of tumor virology (PNAS)
• Ralph Nader recommends The Vertical Farm
• Propose an ASM General Meeting session
• TWiV on Facebook
• Letters read on TWiV 163

Weekly Science Picks

Rich – The Log from the Sea of Cortez by John Steinbeck
Alan – Comet rise
Vincent – TWiV iPhone case

Listener Pick of the Week

Ronnie – How fungi celebrate Christmas
Kevin – EcoCyc app
Gabriel – ImmGen app

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and David Baltimore

Vincent, Alan, and Rich celebrate the 100th episode of TWiV by talking about viruses with Nobel Laureate David Baltimore.

Click the arrow above to play, or right-click to download TWiV #100 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• David’s early papers on poliovirus and mengovirus RNA synthesis
• Reverse transcriptase found by Baltimore and Temin (pdfs)
• Nobel Prize in Physiology or Medicine 1975
• David fishing (Picasa web album)
• The David Baltimore asteroid belt
• Cedric’s essay The ‘Death’ of a Virus (pdf)
• Letters read on TWiV 100

Weekly Science Picks

Alan – TimeTree
Rich – The neurons that shaped civilization
Vincent – Ahead of the Curve: David Baltimore’s Life in Science by Shane Crotty

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson continue virology 101 with a discussion of information flow from RNA to DNA, a process known as reverse transcription, which occurs in cells infected with retroviruses, hepatitis B virus, cauliflower mosaic virus, foamy viruses, and even in uninfected cells.

This episode is sponsored by Data Robotics Inc. To receive $50 off a Drobo or $100 off a Drobo S, visit drobostore.com and use the promotion code VINCENT.

Click the arrow above to play, or right-click to download TWiV #66 (50 MB .mp3, 68 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• Discovery of RNA tumor viruses
• Reverse transcriptase found by Temin and Baltimore (pdfs)
• Figures for this episode
• Video of this episode – download .mp4 or .wmv or view below

Weekly Science Picks
Vincent Joint UN Programme on HIV/AIDS

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.