Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich discuss growth in culture of newly identified rhinovirus C, vaccinia transmission among wrestlers and martial artists, and results of phase III clinical trial of boceprevir, a new inhibitor of hepatitis C virus replication.

Click the arrow above to play, or right-click to download TWiV #130 (45 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Growth of newly identified rhinovirus C (Nature Medicine)
• Global distribution of rhinovirus C (EID)
• Vaccinia transmission among wrestlers (EID)
• Vaccine transmission in a martial arts gym (EID)
• Boceprevir for untreated HCV infection (NEJM)
• Boceprevir for previously treated HCV infection (NEJM)
• HCV antiviral pipeline
• The good viruses (Nat Rev Micro)
• TWiV on Facebook
• Letters read on TWiV 130

Weekly Science Picks

Rich – Rock-paper-scissors vs computer (thanks, Megan!)
Alan – WebCite
Vincent – Edward Jenner Museum (EID)

Listener Pick of the Week

Derek Tolly  - A Paralyzing Fear: The Story of Polio in America (IMDb)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Rich Condit

Vincent, Alan, Dickson and Rich answer listener questions about XMRV, yellow fever vaccine, virus-like particles, West Nile virus, amyotrophic lateral sclerosis and human endogenous retroviruses, multiplicity of infection, and how to make a poxvirus.

Click the arrow above to play, or right-click to download TWiV #129 (67 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• HTLV-2 sequences in patients with CFIDS
• Self-assembling virus (YouTube)
• BookFinder
• Ilya’s photo (jpg)
• Discussion about CROI at ViroBlogy
• Land cover and West Nile virus disease (Am Journ Trop Med Hyg)
• Construction of recombinant poxviruses (Methods Mol Biol)
• Geographic Information System
• TWiV on Facebook
• Letters read on TWiV 129

Weekly Science Picks

Rich – Polyxeni Potter and EID covers
Dickson – American Museum of Natural History
Alan – Moon Trees (EurekAlert! article)
Vincent – Infection Landscapes

Listener Picks of the Week

Didier  - The Vaccines (MySpace)
/Sven-Urban – The Science of Discworld by Terry Pratchett
Garren – Omega Tau podcast

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Grant McFadden

Vincent, Dickson, Alan, Rich, and Grant discuss a tanapoxvirus protein that inhibits tumor necrosis factor, purging tumors with myxoma virus, and destruction of the last known stocks of smallpox virus.

Click the arrow above to play, or rightight click to download TWiV #124 (74 MB .mp3, 103 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Interaction of tumor necrosis factor with tanapox virus protein
• Viron Therapeutics Inc
• Oncolytic viral purging with myxoma virus
• Why not destroy remaining smallpox stocks? (editorial)
• US should agree to destroy smallpox stocks (CIDRAP)
• TWiV on Facebook
• Letters read on TWiV 124

Weekly Science Picks

Grant – A Short History of Nearly Everything by Bill Bryson
Dickson – An Inquiry into the Causes and Effects of the Variolae Vaccinae by Edward Jenner
Rich – Selinah (Topsy Foundation) thanks Meghan!
Alan – Draft report (pdf) on WHO’s H1N1 response and NY Times summary
Vincent – 10 stunning science visualizations

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Ed Niles

Vincent, Rich, and Ed discuss the transition from academic scientist to government work, the general program of drug and vaccine development in the biodefense world and at BARDA, and career opportunities for scientists in government.

Click the arrow above to play, or right click to download TWiV #120 (77 MB .mp3, 147 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• ACAM2000 smallpox vaccine
• Bavarian Nordic’s smallpox vaccine Imvamune and phase II trial
• Rich and Ed’s paper on bacteriophage T7 mRNAs
• Quandaries of dengue vaccine development
• Tetravalent dengue vaccine
• VIVA – virology at Vassar
• TWiV on Facebook
• Letters read on TWiV 120

Weekly Science Picks

Rich – Dark Sun: The Making of the Hydrogen Bomb by Richard Rhodes
Ed – Tenth anniversary of the human genome at Science Magazine
Vincent – Poliovirus fights back

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

The entire TWiV family reviews the latest ideas about colony collapse disorder of honeybees, and resurgence of monkeypox in Africa.

Click the arrow above to play, or right-click to download TWiV #104 (70 MB .mp3, 97 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• The Harvey Lectures
• Iridovirus and microsporidian linked to colony collapse disorder
• CCD discussed previously on TWiV 64, 49, and 46
• Why are they called iridoviruses?
• Iridoviruses at ViralZone
• Scientists and soldiers solve a bee mystery (NY Times, pdf)
• Edgewood research center involvement in CCD
• Resurgence of monkeypox in Africa (PNAS)
• Orthopoxvirus in Ghana
• Outbreak of monkeypox in US (MMWR)
• Goodbye smallpox vaccination, hello monkeypox
• Letters read on TWiV 104

Weekly Science Picks

Dickson – Four Fish by Paul Greenberg
Alan – Nikon Small World contest, 2010 winners
Rich – Encyclopedia of Life
Vincent – First all-digital science textbook will be free (thanks, @windsurfer)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Eric F. Donaldson

Vincent, Alan, Rich and Eric discuss identification of viruses in Northeastern American bats, vaccinia virus infection after sexual contact with a military vaccinee, and identification of a new flavivirus from an Old World bat in Bangladesh.

Click the arrow above to play, or right-click to download TWiV #90 (64 MB .mp3, 89 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Vaccinia virus infection after sexual contact with vaccinee
• Smallpox vaccination overview
• Smallpox vaccine lesions (jpg)
• Smallpox hospital, Roosevelt Island, NY (photo 1, photo 2)
• Isolation of a flavivirus from bats in Bangladesh (PLoS Pathogens)
• Review on hepatitis G virus
• Dickson has been teaching at Singularity University and fishing in Bozeman MT (jpg)
• Letters read on TWiV 90

Weekly Science Picks

Eric – Year of Darwin by Sean Carroll
Rich – March of the Penguins
Alan – Standing-height desks
Vincent – DengueWatch (thanks Richard!)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kirsten Sanford

Vincent, Alan, Rich, and special guest Dr. Kirsten Sanford talk about her career in science media, then consider whether smallpox eradication led to the AIDS pandemic, high fidelity RNA synthesis, and a new Ebola virus vaccine.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #83 (66 MB .mp3, 91 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• Does smallpox vaccine protect against HIV? (thanks, Srinivas; Washington Post and BMC Immunology)
• Was the deltaCRR5 mutation fixed in the human population by smallpox?
• A proofreader in the SARS coronavirus genome
• New ebola vaccine protects monkeys
• House of Numbers trailer, website, Wikipedia article (thanks, Levi!)
• Letters read on TWiV 83

Weekly Science Picks

Alan – Evernote
Rich - The Knife Man by Wendy Moore
Vincent - The Pump Handle

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Matthew Frieman

Vincent, Alan, and Matt review contamination of Rotarix with circovirus DNA, antigenic similarity between 1918 and 2009 H1N1 influenza, a collection of rabies reports, and chicken pox mistaken for smallpox in Uganda.

This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $50 off a Drobo or $100 off a Drobo S.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #75 (57 MB .mp3, 79 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• Contamination of Rotarix vaccine with porcine circovirus 1 DNA
• Beak and feather disease circovirus (BFDV) threatens parrots
• Antigenic similarity between 1918 and 2009 H1N1 influenza
• Presumptive abortive human rabies in Texas
• Rabies rampant: feline, immunization change, Indonesia, wolf, Texas bat, US equine (thanks, Lenn!)
• Austin free tailed bats emerging at dusk
• Suspected smallpox in Uganda
• T-cell receptor therapy for AIDS (thanks Dorian!)

Weekly Science Picks

Matt Bitesize Bio
Alan Free printable graph paper (see also doane paper)
Vincent Avian Flu Diary

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich talk about US government contract for freeze-dried smallpox vaccine, red squirrels in the UK threatened by poxvirus, and Marseillevirus, another DNA virus from amoebae built for comfort and speed.

Sponsor: Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #63 (64 MB .mp3, 89 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• US Government awards contract to Bavarian Nordic for freeze-dried smallpox vaccine (pdf and clinical trial)
• UK red squirrels threatened by poxvirus: news article one and two, epidemiology and experimental infection
• Another huge virus from amoebae (Wired article, PNAS article, review article)
• Discussion on rabies bait vaccine at virology blog, and status of the program
• List of human viral diseases (pdf)

Weekly Science Picks
Rich Infectious Awearables
Alan Darwine
Vincent Microbial Art

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Stephen Morse

Vincent, Alan, and Stephen Morse discuss progressive vaccinia in a smallpox vaccinee, arsenic and influenza in mice, facemasks and flu transmission, and antigenic and genetic analyses of the new H1N1 influenza virus.

Sponsor:  Try GotoMyPC free for 30 days! For this special offer, visit www.gotomypc.com/podcast

Click the arrow above to play, or right-click to download TWiV #34 (54 MB .mp3, 78 minutes)

Links for this episode:

Weekly Science Picks
Alan Org-Mode
Vincent Human/Swine A/H1N1 Influenza Origins and Evolution
Stephen The Origin of Species by Charles Darwin

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Subscribe to TWiV in iTunes, by the RSS feed, or by email