This Week in Virology » TWiV

TWiV 166: Breaking and entering

Vincent Racaniello — Sun, 15 Jan 2012 16:42:11 +0000

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan review cell proteins essential for entry of hepatitis C, Ebola, and measles viruses.

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Click the arrow above to play, or right-click to download TWiV 166 (59 MB .mp3, 98 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

Niemann-Pick C1 is entry factor for HCV (Nature Med)
Ebola virus entry requires Niemann-Pick C1 (Nature one, two)
Nectin-4 is measles virus epithelial receptor (Nature, PLoS Pathogens)
An exit strategy for measles virus (Science)
On this day in history
TWiV on Facebook
Letters read on TWiV 166

Weekly Science Picks

Dickson – What are you swimming with?
Rich – Twelve monkeys
Alan – Kindle Touch
Vincent – Microbe news (thanks to Dave Winer)

Listener Pick of the Week

Eric – The Nature of Things with David Suzuki
Lance – Trials and Errors (Wired)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 144: HIV gets the (zinc) finger

Vincent Racaniello — Sun, 31 Jul 2011 15:10:03 +0000

Hosts: Vincent Racaniello, Rich Condit, and Alan Dove

Vincent, Rich, and Alan discuss live blogging of scientific meetings, the current outbreak of Hendra virus is Australia, and using zinc finger nucleases to make HIV-resistant CD4 cells.

Click the arrow above to play, or right-click to download TWiV 144 (75 MB .mp3, 104 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

Live blogging scientific meetings (virology blog)
Cross reactive Hendra antibodies in dog (article one and two and three)
Dog owner replies
Map of Hendra virus outbreak 2011
Summaries of current Hendra virus outbreak (one and two)
Recombinant Hendra glycoprotein vaccine protects ferrets (Vaccine)
Making HIV resistant CD4 cells with zinc finger nucleases (PLoS Pathogens)
Surveyor nuclease assay
NCIS ‘Toxic’ summary
TWiV on Facebook
Letters read on TWiV 144

Weekly Science Picks

Alan – Bugscope
Rich – Vaccine adverse events: Causal or coincidental? (Lancet)
Vincent – West Nile Story by Dickson Despommier (Kindle edition)

TWiV 127: Viruses are no joke

Vincent Racaniello — Sun, 03 Apr 2011 18:51:47 +0000

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich explore a novel bunyavirus isolated in China, the recent polio outbreak in Republic of the Congo, and cell to cell transmission of a retrovirus by biofilm-like extracellular assemblies.

Click the arrow above to play, or right-click to download TWiV #127 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

Novel bunyavirus isolated in China (NEJM)
Bunyavirus page at ViralZone
Polio outbreak, Republic of the Congo (MMWR)
Poliovirus isolation from Republic of the Congo polio outbreak (Eurosurveillance)
HTLV-1 transmission by biofilm-like extracellular assemblies (Nature Medicine)
TWiV on Facebook
Letters read on TWiV 127

Weekly Science Picks

Rich – Should smallpox be destroyed? (Emerging Infectious Diseases)
Alan – Zoology of the Beagle images
Vincent – Vaccines and Your Child by Paul Offit and Charlotte Moser

TWiV 111: Live at Florida Gulf Coast University

Vincent Racaniello — Mon, 13 Dec 2010 03:07:39 +0000

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Ed Fussell, Andrea Leal, and Amy Sargent

The TWiV crew meets with members of the Florida Keys Mosquito Control District at Florida Gulf Coast University to discuss dengue in Florida and how to control it.

Click the arrow above to play, or right-click to download TWiV #111 (76 MB .mp3, 105 minutes). To download, right-click or control-click on the link, then select save as.

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

Florida Keys Mosquito Control District
Prof. Sharon Isern
Florida Gulf Coast University
CDC report on dengue in the Florida Keys
Dengue in Miami
Mosquito release in the Caymans (Oxitec press release - pdf)
Concerns about mosquito release
TWiV on Facebook – photos of TWiV 111
Letters read on TWiV 111
Video of this episode – Download .mp4 (136 MB) or .wmv (457 MB) or view below

Weekly Science Picks

Rich – At the Bench, A Laboratory Navigator by Kathy Barker
Alan – DEEP Indonesia Underwater Photo Contest 2010 Winners
Vincent – HHMI resources for early-career scientists

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 108: Barking up the right Tre

Vincent Racaniello — Sun, 21 Nov 2010 21:52:09 +0000

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Saul Silverstein

Vincent, Alan, Rich, and Saul review the evolution of HIV-1 specific recombinases, and down-regulation of a host microRNA by a viral noncoding RNA.

Click the arrow above to play, or right-click to download TWiV #108 (64 MB .mp3, 89 minutes). To download, right-click or control-click on the link, then select save as.

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

HIV-1 proviral excision with an evolved recombinase
Evolution of HIV-1 specific recombinases – review article
Down-regulation of a host miRNA by a viral noncoding RNA
Paring miRNAs through pairing – commentary
GM mosquitoes wipe out dengue
Virology faculty position, University of Maryland
TWiV on Facebook
Letters read on TWiV 108

Weekly Science Picks

Rich – Where cinema and biology meet
Alan – Qiagen iApp
Vincent – Ask a biologist

TWiV 103: Shots with LJ Tan

Vincent Racaniello — Sun, 17 Oct 2010 19:29:02 +0000

Hosts: Vincent Racaniello, Alan Dove, and LJ Tan

Vincent and Alan discuss influenza vaccines with LJ Tan of the American Medical Association.

Click the arrow above to play, or right-click to download TWiV #103 (56 MB .mp3, 77 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

The American Medical Association
Prevent Influenza Now
Vaccine injury claim reaches Supreme Court
Supreme Court divided on vaccine case
No narcolepsy link to flu vaccine
Letters read on TWiV 103

Weekly Science Picks

Alan – BioGene, an iApp
Vincent – The Vertical Farm by Dickson Despommier

TWiV 101: Sizing up adenovirus

Vincent Racaniello — Sun, 03 Oct 2010 16:08:15 +0000

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Dickson Despommier, and Hamish Young

Vincent, Alan, Rich, Dickson, and Hamish review the three-dimensional structure of adenovirus, and the role of adenovirus type 36 in obesity.

Click the arrow above to play, or right-click to download TWiV #101 (55 MB .mp3, 76 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

Three-dimensional structure of adenovirus solved by x-ray crystallography and Cryo-EM
Movies of adenovirus
Commentary on adenovirus structure
Adenovirus picture book
Adenovirus type 36 and obesity in children and adolescents
Press release on adenovirus 36 and obesity
How much TWiV do you want? Take the survey
Pre-order The Vertical Farm by Dickson Despommier
Letters read on TWiV 101

Weekly Science Picks

Alan – National Geographic’s Best Environmental Photographs of 2010
Rich – Richard Feynman lecture: The pleasure of finding things out
Vincent – Summary of the First International XMRV Workshop (pdf)

TWiV 100: TWiV catches a big fish

Vincent Racaniello — Sun, 26 Sep 2010 16:12:27 +0000

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and David Baltimore

Vincent, Alan, and Rich celebrate the 100th episode of TWiV by talking about viruses with Nobel Laureate David Baltimore.

Click the arrow above to play, or right-click to download TWiV #100 (68 MB .mp3, 94 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

David’s early papers on poliovirus and mengovirus RNA synthesis
Reverse transcriptase found by Baltimore and Temin (pdfs)
Nobel Prize in Physiology or Medicine 1975
David fishing (Picasa web album)
The David Baltimore asteroid belt
Cedric’s essay The ‘Death’ of a Virus (pdf)
Letters read on TWiV 100

Weekly Science Picks

Alan – TimeTree
Rich – The neurons that shaped civilization
Vincent – Ahead of the Curve: David Baltimore’s Life in Science by Shane Crotty

TWiV 99: ICAAC Boston 2010

Vincent Racaniello — Mon, 20 Sep 2010 01:45:02 +0000

Host: Vincent Racaniello

On episode 99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston, speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure.

Many thanks to Chris Condayan and Ray Ortega of the American Society for Microbiology for recording and editing this episode.

Click the arrow above to play, or right-click to download TWiV #99 (45 MB .mp3, 62 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

50th ICAAC
ICAAC daily press conference videos (including Prof. Myra McClure)
Antigenic cartography
Antimicrobial properties of copper
Video of this episode – download .mp4 (1.99 GB) or .wmv (935 MB) or view below

TWiV 98: Murine musings, electric shirts, and rabid pathologists

Vincent Racaniello — Sun, 12 Sep 2010 10:23:43 +0000

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Click the arrow above to play, or right-click to download TWiV #98 (58 MB .mp3, 80 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

MLV-related sequences in blood of CFS patients (commentary)
Laboratory inventories for poliovirus containment
Viral batteries for the military (abstract) – also see TWiV 28
Human rabies, Kentucky/Indiana, 2009
Letters read on TWiV 98

Weekly Science Picks

Alan – NCBI ROFL
Rich – The Great Bridge by David McCullough
Vincent – Dr. Rous’ Prize-Winning Chicken