Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

Vincent, Dickson, Rich, and Alan answer listener questions about XMRV, cytomegalovirus, latency, shingles vaccine, myxomavirus and rabbits, and more.

Please help us by taking our listener survey.

Click the arrow above to play, or right-click to download TWiV 165 (61 MB .mp3, 102 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Human CMV incorporates antibody into virions (Cell Host Microbe)
• Probing influenza virion with a supercomputer (Chinese Sci Bull)
• Hallmarks of cancer (Cell)
• Dr. Eric Schadt talk, Mt. Sinai
• Bacteriophage T4 tattoo
• Virology meme
• Sociedad Española de Virología
• Norovirus takes to the skies (Sci Am) and journal article (Clin Inf Dis)
• Propose an ASM General Meeting session
• TWiV on Facebook
• Letters read on TWiV 165

Weekly Science Picks

Dickson – Creation
Rich – America’s Science Decline
Alan – Out of context science
Vincent – The Scientist Top 10 Innovations 2011

Listener Pick of the Week

Jim – Christoph Adami: Finding life we can’t imagine (TED)
Tim – Patient Zero (Radiolab)
Mary – Natural Obsessions by Natalie Angier
Jimmy – Science Exchange

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Alan Dove

Vincent, Alan, and Rich review ten compelling virology stories of 2011.

Please help us by taking our listener survey.

Click the arrow above to play, or right-click to download TWiV 164 (60 MB .mp3, 99 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Ten virology stories of 2011:

1. XMRV, CFS, and prostate cancer (TWiV 119, 123, 136, 150)
2. Influenza H5N1, ferrets, and the NSABB (TWiV 159)
3. The Panic Virus (TWiV 117)
4. Polio eradication (TWiV 127, 149)
5. Viral oncotherapy (TWiV 124, 131, 142, 156)
6. Hepatitis C virus (TWiV 130, 137, 141)
7. Zinc finger nuclease and HIV therapy (TWiV 144)
8. Bacteria help viruses (TWiV 154)
9. Human papillomaviruses (TWiV 126)
10. Combating dengue with Wolbachia (TWiV 115, 147)

Links for this episode:

• Honorable mention: Color me infected (TWiV 115)
• Lo-Alter retraction (PNAS)
• Propose an ASM General Meeting session
• TWiV on Facebook
• Letters read on TWiV 164

Weekly Science Picks

Rich - Fundamentals of Molecular Virology by Nicholas H. Acheson
Alan – Fetch, with Ruff Ruffman
Vincent – Year end reviews at Rule of 6ix and Contagions

Listener Pick of the Week

Garren – Trillion-frame-per-second video
Judi – iBioMagazine
Ricardo – Brain Picking’s 11 best science books of 2011

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Dickson Despommier

Vincent, Dickson, and Rich meant to do an all-email episode, but first they review results of the Blood XMRV Scientific Research Working Group, and partial retraction of the paper associating XMRV with chronic fatigue syndrome.

With this episode TWiV is three years old.

Click the arrow above to play, or right-click to download TWiV 150 (56 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Partial retraction (Science)
• Failure to confirm (Science)
• False positive (Science)
• Why a partial retraction? (Retraction Watch)
• TWiV on Facebook
• Letters read on TWiV 150

Weekly Science Picks

Dickson – The Tree of Life
Vincent – When do you fact-check article content with sources? (take as directed)
Rich – io9

Listener Pick of the Week

Luis – NIH videocasting and podcasting

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Stephen Goff

Retrovirologist Stephen Goff joins Vincent, Rich, and Alan for a discussion of recent papers on the retrovirus XMRV and its association with chronic fatigue syndrome and prostate cancer.

Click the arrow above to play, or right-click to download TWiV #136 (61 MB .mp3, 84 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Recombinant origin of XMRV (Science Express)
• No evidence of gammaretroviruses in XMRV-positive CFS patients (Science Express)
• Editorial expression of concern (Science)
• Absence of XMRV in CFS patients (J Virology)
• TWiV on Facebook
• Letters read on TWiV 136

Weekly Science Picks

Alan – The Demon-Haunted World by Carl Sagan
Rich – Trends in annual rates of death (pdf)
Stephen – Unexpected inheritance (PLoS Pathogens)
Vincent – Beyond the human eye

Listener Pick of the Week

Raihan  - Bruce Aylward: How we’ll stop polio for good (YouTube)

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Rich Condit

Vincent, Alan, Dickson and Rich answer listener questions about XMRV, yellow fever vaccine, virus-like particles, West Nile virus, amyotrophic lateral sclerosis and human endogenous retroviruses, multiplicity of infection, and how to make a poxvirus.

Click the arrow above to play, or right-click to download TWiV #129 (67 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• HTLV-2 sequences in patients with CFIDS
• Self-assembling virus (YouTube)
• BookFinder
• Ilya’s photo (jpg)
• Discussion about CROI at ViroBlogy
• Land cover and West Nile virus disease (Am Journ Trop Med Hyg)
• Construction of recombinant poxviruses (Methods Mol Biol)
• Geographic Information System
• TWiV on Facebook
• Letters read on TWiV 129

Weekly Science Picks

Rich – Polyxeni Potter and EID covers
Dickson – American Museum of Natural History
Alan – Moon Trees (EurekAlert! article)
Vincent – Infection Landscapes

Listener Picks of the Week

Didier  - The Vaccines (MySpace)
/Sven-Urban – The Science of Discworld by Terry Pratchett
Garren – Omega Tau podcast

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes.

Click the arrow above to play, or rightight click to download TWiV #123 (67 MB .mp3, 93 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Analysis of XMRV integration sites from human prostate cancer (Retrovirology)
• Integration site preference of XMRV (J Virology)
• The Decline Effect and the Scientific Method by Jonathan Lehrer (New Yorker)
• Why most published research findings are false (PLoS Medicine)
• Cochrane Reviews
• Richard Feynman’s 1974 Caltech Commencement Address (pdf) (thanks, Bill!)
• First virus of Caenorhabditis (PLoS Biology)
• Nodaviruses at ViralZone
• Spandrels (thanks, Welkin!)
• TWiV on Facebook
• Letters read on TWiV 123

Weekly Science Picks

Rich – Einstein: His Life and Universe by Walter Isaacson (Aspen Institute)
Alan – Hi-definition microscopy movies in 3D
Vincent – Stan Maloy interview with Beatrice Hahn on the origins of HIV and malaria

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich revisit ten compelling virology stories of 2010.

Click the arrow above to play, or right click to download TWiV #114 (64 MB .mp3, 88 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Ten virology stories of 2010:

1. XMRV, CFS, and prostate cancer (TWiV 113, 99, 98, 94, 89, 76, 70, 65)
2. The ongoing saga of polio eradication (TWiV 110, 79)
3. Viruses interact with the miRNA/siRNA system (TWiV 108, 72)
4. Endogenous viruses – retro and beyond (TWiV 105, 91, 88, 65)
5. Dengue virus progress and new outbreak (TWiV 111, 95, 82)
6. Colony collapse disorder (TWiV 104)
7. David Baltimore (TWiV 100)
8. Ode to a plaque (TWiV 68)
9. Vaccine contamination with circovirus (TWiV 86, 77, 75)
10. Universal influenza vaccines (TWiV 107)

Weekly Science Picks

Rich – Elementary schoolchildren publish a science paper (original article and editorial with video) – thanks Kathy!
Alan – White-nose syndrome blog
Vincent – Headway, headlines and healthy skepticism

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Alan Rein

Vincent, Alan, and Rich discuss the retrovirus XMRV with retrovirologist Alan Rein of the National Cancer Institute.

Click the arrow above to play, or right-click to download TWiV #113 (55 MB .mp3, 76 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• XMRV: A new virus is prostate cancer? (Cancer Research)
• Detection of XMRV in normal and prostate tumor tissue (J Inf Dis)
• Reach for a scorecard (commentary, J Inf Dis)
• Retrovirology papers: one, two, three, four, commentary
• Integration sites of XMRV in prostate tumor DNA (J Virol, PLoS One)
• TWiV on Facebook
• Letters read on TWiV 113

Weekly Science Picks

Rich – Word Lens
Alan – Tetenal Press Kit
Vincent – In the pipeline and Things I won’t work with by Derek Lowe

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Host: Vincent Racaniello

On episode 99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston, speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure.

Many thanks to Chris Condayan and Ray Ortega of the American Society for Microbiology for recording and editing this episode.

Click the arrow above to play, or right-click to download TWiV #99 (45 MB .mp3, 62 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• 50th ICAAC
• ICAAC daily press conference videos (including Prof. Myra McClure)
• Antigenic cartography
• Antimicrobial properties of copper
• Video of this episode – download .mp4 (1.99 GB) or .wmv (935 MB) or view below

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Click the arrow above to play, or right-click to download TWiV #98 (58 MB .mp3, 80 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio.

Links for this episode:

• MLV-related sequences in blood of CFS patients (commentary)
• Laboratory inventories for poliovirus containment
• Viral batteries for the military (abstract) – also see TWiV 28
• Human rabies, Kentucky/Indiana, 2009
• Letters read on TWiV 98

Weekly Science Picks

Alan – NCBI ROFL
Rich – The Great Bridge by David McCullough
Vincent – Dr. Rous’ Prize-Winning Chicken

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.